SCHEMBL377078

SCHEMBL377078

C=CCN(O)c1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.45
CYP1A2 P05177 1/20 0.43
S1PR1 P21453 1/20 0.40
KMT2A Q03164 4/20 0.39
MEN1 O00255 3/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
KDM4E B2RXH2 2/20 0.39
TSHR P16473 2/20 0.38
ALDH1A1 P00352 6/20 0.38
GLA P06280 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.37
HPGD P15428 2/20 0.36
ATM Q13315 1/20 0.36
POLB P06746 2/20 0.35
LMNA P02545 1/20 0.35
ALOX12 P18054 1/20 0.35
CCR6 P51684 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10588571 0.88 CYP1A2 (0.34) ESR1CYP1A2SMN1; SMN2TSHR
SCHEMBL6255892 0.78 ALDH1A1 (0.39) CYP1A2KMT2AMEN1KDM4ETSHR
SCHEMBL39946 0.78 ESR1 (0.44) ESR1CYP1A2S1PR1KMT2AMEN1
Benzene SCHEMBL27985319 0.78 ESR1 (0.44) ESR1CYP1A2S1PR1KMT2AMEN1
SCHEMBL9818045 0.78 ESR1 (0.44) ESR1CYP1A2S1PR1KMT2AMEN1
SCHEMBL83762 0.76 CHKA (0.46) ESR1CYP1A2S1PR1KMT2AMEN1
Water SCHEMBL10786878 0.76 ESR1 (0.43) ESR1CYP1A2S1PR1KMT2AMEN1
Ammonia Solution, Strong SCHEMBL28398668 0.76 ESR1 (0.43) ESR1CYP1A2S1PR1KMT2AMEN1
SCHEMBL11032897 0.76 CHKA (0.46) ESR1CYP1A2S1PR1KMT2AMEN1
Methane SCHEMBL27634949 0.76 ESR1 (0.43) ESR1CYP1A2S1PR1KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 175 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120040658-A Self-thickening polyacrylamide and preparation method and application thereof 中海油田服务股份有限公司 2025-05-27 CN claimed
EP-1414803-B1 PYRAZOLYLCARBOXANILIDES AS FUNGICIDES BAYER CROPSCIENCE AG (DE) 2012-12-12 EP claimed
US-7652022-B2 N-(4-(4-(4-hydroxyphenylamino)-pyrimidin-6-yl)-oxyphenyl)-N'-(3-trifluoromethylphenyl)-urea; NOVARTIS AG (CH) 2010-01-26 US claimed
EP-1511730-B8 DIARYL UREA DERIVATIVES USEFUL FOR THE TREATMENT OF PROTEIN KINASE DEPENDENT DISEASES NOVARTIS AG (CH) 2009-04-08 EP claimed
US-20060128734-A1 Diaryl urea derivatives useful for the treatment of protein kinase dependent diseases FLOERSHEIMER ANDREAS 2006-06-15 US claimed
EP-1511730-A2 DIARYL UREA DERIVATIVES USEFUL FOR THE TREATMENT OF PROTEIN KINASE DEPENDENT DISEASES Novartis AG (CH) 2005-03-09 EP claimed
US-20040204470-A1 Pyrazoylcarboxanilides as fungicides BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2004-10-14 US claimed
WO-2003099771-A2 DIARYL UREA DERIVATIVES USEFUL FOR THE TREATMENT OF PROTEIN KINASE DEPENDENT DISEASES NOVARTIS AG (CH) 2003-12-04 WO claimed
US-20030225087-A1 N-alkyl-N-phenylhydroxylamine compounds containing metal chelating groups, their preparation and their therapeutic uses SAM-SUNG ELECTRONICS CO., LTD. (KR) 2003-12-04 US claimed
WO-2003010153-A1 N-ALKYL-N-PHENYLHYDROXYLAMINE COMPOUNDS CONTAINING METAL CHELATING GROUPS, THEIR PREPARATION AND THEIR THERAPEUTIC USES SAMSUNG ELECTRONICS CO. LTD. (KR) 2003-02-06 WO claimed
US-4235730-A DISPERSANTS TEXACO INC. (US) 1980-11-25 US claimed
JP-59010565-A None JP disclosed
JP-52113930-A None JP disclosed
JP-56106600-A None JP disclosed
JP-61122265-A None JP disclosed
US-4391805-A FUNGICIDES, ANTIPROTOZOA AGENTS, BACTERICIDWS HOECHST AKTIENGESELLSCHAFT (DE) 1983-07-05 US disclosed
EP-0050298-A2 1-(1,3-Dioxolan-2-ylmethyl) azoles, process for their preparation and their use HOECHST AKTIENGESELLSCHAFT (DE) 1982-04-28 EP disclosed
JP-S56106600-A NOVEL DETERMINING METHOD OF HYDROGEN PEROXIDE WAKO PURE CHEM IND LTD 1981-08-24 JP disclosed
JP-S52113930-A PREPARATION OF ALKOXYANILINES IHARA CHEM IND CO LTD 1977-09-24 JP disclosed
US-4009201-A PARTIALLY OR FULLY QUATERNIZED POLYAMINE ESTERS OF ACRYLIC ACIDS ALCOLAC INC. (US) 1977-02-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040204470-A1 Pyrazoylcarboxanilides as fungicides CYP1A1, CYP1B1, CYP2E1 ESR1 3865/4885CYP1A2 6/4885S1PR1 2455/4885
US-20030225087-A1 N-alkyl-N-phenylhydroxylamine compounds containing metal chelating groups, their preparation and their therapeutic uses SOD1, LPO, BAD ESR1 2490/4885CYP1A2 2388/4885S1PR1 1644/4885
US-20060128734-A1 Diaryl urea derivatives useful for the treatment of protein kinase dependent diseases UCK2, PRKDC, PRKACA ESR1 4387/4885CYP1A2 3905/4885S1PR1 4315/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.