Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 2/20 | 0.45 |
| ▸ | CDK9 | P50750 | 2/20 | 0.45 |
| ▸ | EGFR | P00533 | 6/20 | 0.45 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | BRAF | P15056 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5813644 | 0.83 | CCNT1 (0.47) | CCNT1CDK9TGFBR1BRAF | |
| SCHEMBL5817990 | 0.81 | PTGDR2 (0.36) | TGFBR1KCNH2 | |
| SCHEMBL5817615 | 0.78 | KCNH2 (0.57) | EGFRKCNH2 | |
| SCHEMBL5818629 | 0.78 | KCNH2 (0.60) | KCNH2 | |
| SCHEMBL30409799 | 0.78 | EGFR (0.49) | CCNT1CDK9EGFRTGFBR1KCNH2 | |
| SCHEMBL29039434 | 0.78 | EGFR (0.49) | CCNT1CDK9EGFRTGFBR1KCNH2 | |
| SCHEMBL5819806 | 0.77 | MAPK13 (0.56) | CCNT1CDK9EGFR | |
| SCHEMBL5819805 | 0.77 | MAPK13 (0.56) | CCNT1CDK9EGFR | |
| SCHEMBL5822178 | 0.73 | EGFR (0.46) | CCNT1CDK9EGFRTGFBR1KCNH2 | |
| SCHEMBL5819107 | 0.70 | ADORA2A (0.38) | KDM4EMAPTBRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006137658-A1 | NEW SUBSTITUTED 1,3-THIAZOLE DERIVATIVES OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF HAVING IMMUNOSUPPRESSION AND INFLAMMATION INHIBITORY ACITIVITY, INTERMEDIATE COMPOUNDS OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF, A PROCESS FOR THE PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | DONGBU HITEK CO., LTD. (KR) | 2006-12-28 | — | — | WO | disclosed |