Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10289399 | 0.82 | PIK3CD (0.48) | PIK3CDLMNARAB9A | |
| SCHEMBL9979979 | 0.82 | PIK3CD (0.38) | PIK3CDRAB9A | |
| SCHEMBL24577158 | 0.79 | ADH1B (0.34) | PIK3CD | |
| SCHEMBL12703399 | 0.74 | KCNA5 (0.43) | PIK3CDRAB9A | |
| SCHEMBL13995359 | 0.72 | PIK3CD (0.50) | PIK3CDALDH1A1RAB9A | |
| SCHEMBL24578095 | 0.72 | PIK3CD (0.40) | PIK3CDRAB9A | |
| SCHEMBL5535641 | 0.72 | PIK3CD (0.40) | PIK3CDRAB9A | |
| SCHEMBL5535647 | 0.72 | PIK3CD (0.40) | PIK3CDALDH1A1KDM4ERAB9A | |
| SCHEMBL11119 | 0.72 | — | — | |
| SCHEMBL7364138 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006075160-A1 | N-PHENYL-4-PYRIDIN-2-YL-BENZAMIDE DERIVATIVES AS HISTONE DEACYLASE (HDAC) INHIBITORS FOR THE TREATMENT OF CANCER | ASTRAZENECA AB (SE) | 2006-07-20 | — | — | WO | disclosed |