Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.36 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.36 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.36 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.36 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10289399 | 0.84 | PIK3CD (0.48) | PIK3CDRAB9A | |
| SCHEMBL25633209 | 0.84 | PRMT3 (0.48) | PRMT3CARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL5819829 | 0.82 | PIK3CD (0.36) | PIK3CDRAB9A | |
| SCHEMBL7368745 | 0.80 | PRMT3 (0.33) | PRMT3CARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL24577158 | 0.77 | ADH1B (0.34) | PIK3CD | |
| SCHEMBL19889818 | 0.77 | TSHR (0.36) | PRMT3CARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL12703399 | 0.76 | KCNA5 (0.43) | PIK3CDRAB9A | |
| SCHEMBL12225829 | 0.76 | PRMT3 (0.40) | PRMT3CARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL5535647 | 0.74 | PIK3CD (0.40) | PIK3CDRAB9A | |
| SCHEMBL13995359 | 0.74 | PIK3CD (0.50) | PIK3CDRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012080456-A1 | BICYCLIC RING SYSTEM SUBSTITUTED AMIDE FUNCTIONALISED PHENOLS AS MEDICAMENTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-06-21 | — | — | WO | disclosed |