Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 5/20 | 0.37 |
| ▸ | DRD3 | P35462 | 4/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 5/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 2/20 | 0.34 |
| ▸ | HTR2A | P28223 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5820088 | 0.84 | SYK (0.39) | DRD2DRD3NPSR1L3MBTL1ALDH1A1 | |
| SCHEMBL4747717 | 0.83 | GRM2 (0.36) | GRM2L3MBTL1ALDH1A1KDM4EMAPT | |
| SCHEMBL5816427 | 0.81 | GRM2 (0.35) | GRM2L3MBTL1ALDH1A1KDM4EMAPT | |
| SCHEMBL5820228 | 0.77 | KCNH2 (0.39) | DRD2DRD3NPSR1ALDH1A1KDM4E | |
| SCHEMBL4907061 | 0.74 | EGFR (0.42) | L3MBTL1ALDH1A1KDM4EMAPTMEN1 | |
| SCHEMBL5814327 | 0.74 | JAK2 (0.43) | NPSR1L3MBTL1MEN1KMT2A | |
| SCHEMBL4750623 | 0.71 | GRM2 (0.40) | DRD2GRM2NPSR1HTR1AHTR2A | |
| SCHEMBL4747891 | 0.69 | SYK (0.39) | GRM2L3MBTL1ALDH1A1KDM4EMAPT | |
| SCHEMBL5814919 | 0.69 | KDM5A (0.33) | GRM2L3MBTL1ALDH1A1KDM4EMAPT | |
| SCHEMBL4788702 | 0.68 | GRM2 (0.36) | GRM2KDM4EMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006112666-A1 | PYRIDINE DERIVATIVES, METHODS OF THEIR PREPARATIONS, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | SK CHEMICALS CO., LTD. (KR) | 2006-10-26 | — | — | WO | claimed |
| WO-2006112666-A1 | PYRIDINE DERIVATIVES, METHODS OF THEIR PREPARATIONS, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | SK CHEMICALS CO., LTD. (KR) | 2006-10-26 | — | — | WO | disclosed |