Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.31 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | FYN | P06241 | 1/20 | 0.30 |
| ▸ | SRC | P12931 | 1/20 | 0.30 |
| ▸ | FLT3 | P36888 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4788702 | 0.89 | GRM2 (0.36) | KDM5AGRM2KDM4EMAPTSLC29A1 | |
| SCHEMBL5816427 | 0.87 | GRM2 (0.35) | KDM5AGRM2HPGDALDH1A1ACKR3 | |
| SCHEMBL5813982 | 0.81 | SYK (0.39) | KDM5AGRM2HPGDALDH1A1ACKR3 | |
| SCHEMBL4749987 | 0.76 | EGFR (0.42) | HPGDALDH1A1KDM4EMAPTMEN1 | |
| SCHEMBL4747371 | 0.75 | NPC1 (0.34) | HPGDALDH1A1KDM4EMAPTL3MBTL1 | |
| SCHEMBL4750208 | 0.72 | JAK2 (0.43) | KDM5AHPGDALDH1A1KDM4EMAPT | |
| SCHEMBL4747717 | 0.71 | GRM2 (0.36) | GRM2ALDH1A1KDM4EMAPTHTT | |
| SCHEMBL5819969 | 0.69 | DRD2 (0.37) | GRM2ALDH1A1KDM4EMAPTHTT | |
| SCHEMBL4747891 | 0.65 | SYK (0.39) | GRM2ALDH1A1KDM4EMAPTHTT | |
| SCHEMBL5820088 | 0.62 | SYK (0.39) | ALDH1A1KDM4EMAPTHTTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006112666-A1 | PYRIDINE DERIVATIVES, METHODS OF THEIR PREPARATIONS, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | SK CHEMICALS CO., LTD. (KR) | 2006-10-26 | — | — | WO | claimed |
| WO-2006112666-A1 | PYRIDINE DERIVATIVES, METHODS OF THEIR PREPARATIONS, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | SK CHEMICALS CO., LTD. (KR) | 2006-10-26 | — | — | WO | disclosed |