Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | AURKA | O14965 | 2/20 | 0.38 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | CDC7 | O00311 | 1/20 | 0.38 |
| ▸ | PLK4 | O00444 | 1/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.38 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.38 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.38 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5818277 | 0.88 | KDM4E (0.38) | KDM4ECYP3A4CYP2C9TDP1RET | |
| SCHEMBL4399145 | 0.85 | GRM5 (0.47) | ELANEPOLBGRM5RAB9AMEN1 | |
| SCHEMBL3961436 | 0.79 | RAB9A (0.42) | KDM4EMAPTRETPOLBRAB9A | |
| SCHEMBL4396431 | 0.75 | KDM4E (0.43) | KDM4ERETKDRDYRK1AGRM5 | |
| SCHEMBL4396419 | 0.74 | PRKAB2 (0.42) | KDM4EMAPTCSF1RRETCDK2 | |
| SCHEMBL4399147 | 0.70 | GRM5 (0.46) | MAPTMAPK1RETKDRPOLB | |
| SCHEMBL5818038 | 0.70 | GRM5 (0.39) | KDM4ECYP3A4CYP2C9MAPTTDP1 | |
| SCHEMBL4792976 | 0.70 | KMT2A (0.47) | KDM4EMAPTTDP1MAPK1L3MBTL1 | |
| SCHEMBL4394525 | 0.69 | RAB9A (0.40) | MAPTPOLBGRM5GRM1L3MBTL1 | |
| SCHEMBL5822526 | 0.69 | TP53 (0.49) | KDM4EMAPTPOLBNPSR1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006124897-A2 | METHODS AND COMPOSITIONS FOR IMPROVING COGNITION | LEXICON GENETICS INCORPORATED (US) | 2006-11-23 | — | — | WO | disclosed |