Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.64 |
| ▸ | NPC1 | O15118 | 4/20 | 0.64 |
| ▸ | PHGDH | O43175 | 1/20 | 0.52 |
| ▸ | MGLL | Q99685 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10282539 | 0.80 | ALDH1A1 (0.67) | ALDH1A1NPC1PHGDHMGLLKMT2A | |
| SCHEMBL2606048 | 0.80 | ALDH1A1 (0.67) | ALDH1A1NPC1PHGDHMGLLKMT2A | |
| SCHEMBL13663831 | 0.78 | ALDH1A1 (0.64) | ALDH1A1NPC1PHGDHMGLLKMT2A | |
| SCHEMBL8284598 | 0.78 | ALDH1A1 (0.64) | ALDH1A1NPC1PHGDHMGLLKMT2A | |
| SCHEMBL1120405 | 0.78 | ALDH1A1 (0.64) | ALDH1A1NPC1PHGDHMGLLKMT2A | |
| SCHEMBL5803887 | 0.78 | ALDH1A1 (0.64) | ALDH1A1NPC1PHGDHMGLLKMT2A | |
| SCHEMBL15337702 | 0.78 | ALDH1A1 (0.64) | ALDH1A1NPC1PHGDHMGLLKMT2A | |
| SCHEMBL6417845 | 0.78 | ALDH1A1 (0.64) | ALDH1A1NPC1PHGDHMGLLKMT2A | |
| SCHEMBL229527 | 0.78 | ALDH1A1 (1.00) | ALDH1A1NPC1PHGDHMGLLKMT2A | |
| SCHEMBL13451572 | 0.77 | ALDH1A1 (0.62) | ALDH1A1NPC1PHGDHMGLLKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006093518-A2 | THIENYL COMPOUNDS FOR TREATING VIRUS-RELATED CONDITIONS | APATH, LLC (US) | 2006-09-08 | — | — | WO | disclosed |