Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 1.00 |
| ▸ | NPC1 | O15118 | 4/20 | 0.64 |
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | PHGDH | O43175 | 1/20 | 0.47 |
| ▸ | MGLL | Q99685 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 5/20 | 0.45 |
| ▸ | YAP1 | P46937 | 1/20 | 0.45 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11839944 | 0.92 | ALDH1A1 (0.85) | ALDH1A1NPC1LMNAKMT2AMEN1 | |
| SCHEMBL11837759 | 0.88 | ALDH1A1 (0.79) | ALDH1A1NPC1LMNAKMT2AMEN1 | |
| SCHEMBL23144550 | 0.80 | ALDH1A1 (0.67) | ALDH1A1NPC1LMNAKMT2AMEN1 | |
| SCHEMBL5564424 | 0.80 | ALDH1A1 (0.67) | ALDH1A1NPC1LMNASMN1; SMN2POLB | |
| SCHEMBL10282539 | 0.80 | ALDH1A1 (0.67) | ALDH1A1NPC1LMNAKMT2AMEN1 | |
| SCHEMBL2606048 | 0.80 | ALDH1A1 (0.67) | ALDH1A1NPC1LMNAKMT2AMEN1 | |
| SCHEMBL24549628 | 0.79 | ALDH1A1 (0.66) | ALDH1A1NPC1LMNASMN1; SMN2POLB | |
| SCHEMBL6417845 | 0.78 | ALDH1A1 (0.64) | ALDH1A1NPC1LMNAKMT2AMEN1 | |
| SCHEMBL8284598 | 0.78 | ALDH1A1 (0.64) | ALDH1A1NPC1LMNAKMT2AMEN1 | |
| SCHEMBL5820296 | 0.78 | ALDH1A1 (0.64) | ALDH1A1NPC1LMNAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119874601-A | 3, 3-Dimethyl-1, 2,3, 4-tetrahydro-9H-carbazole derivative and preparation method and application thereof | 山东大学 | 2025-04-25 | — | — | CN | claimed |
| US-20250368608-A1 | SELECTIVE HDAC6 INHIBITOR | ROYAL COLLEGE OF SURGEONS IN IRELAND (IE) | 2025-12-04 | — | — | US | disclosed |
| CN-119874601-A | 3, 3-Dimethyl-1, 2,3, 4-tetrahydro-9H-carbazole derivative and preparation method and application thereof | 山东大学 | 2025-04-25 | — | — | CN | disclosed |
| CN-115466253-B | Oxazolidinone compound containing dithiocarbamic acid ester structure and preparation method thereof | 沈阳药科大学 | 2024-08-20 | — | — | CN | disclosed |
| CN-115466253-A | Oxazolidinone compound containing dithiocarbamate structure and preparation method thereof | 沈阳药科大学 | 2022-12-13 | — | — | CN | disclosed |
| WO-2022129256-A1 | SELECTIVE HDAC6 INHIBITOR | ROYAL COLLEGE OF SURGEONS IN IRELAND (IE) | 2022-06-23 | — | — | WO | disclosed |
| US-11332459-B2 | Benzimidazole derivatives and their uses | TEIJIN PHARMA LIMITED (JP) | 2022-05-17 | — | — | US | disclosed |
| US-20200308145-A1 | BENZIMIDAZOLE DERIVATIVES AND THEIR USES | AMGEN INC. (US) | 2020-10-01 | — | — | US | disclosed |
| US-9481676-B2 | Azepino[4,5-B]indoles and methods of use | MEDIVATION TECHNOLOGIES, INC. (US) | 2016-11-01 | — | — | US | disclosed |
| US-9469641-B2 | Pyrido[3,4-B]indoles and methods of use | MEDIVATION TECHNOLOGIES, INC. (US) | 2016-10-18 | — | — | US | disclosed |
| US-20090270412-A1 | PYRIDO[3,4-B]INDOLES AND METHODS OF USE | MEDIVATION TECHNOLOGIES, INC. | 2009-10-29 | — | — | US | disclosed |
| WO-2009120094-A2 | SUBSTITUTED PYRIMIDINES AND TRIAZINES AND THEIR USE IN CANCER THERAPY | AUCKLAND UNISERVICES LIMITED (NZ) | 2009-10-01 | — | — | WO | disclosed |
| EP-1497265-B1 | COMPOUNDS HAVING AFFINITY AT 5HT2C RECEPTOR AND USE THEREOF IN THERAPY | GLAXO GROUP LTD (GB) | 2009-02-18 | — | — | EP | disclosed |
| US-20060116364-A1 | Such as (R)-6-{2-{ethyl[4-(2-ethylaminoethyl)benzyl]amino }-4-methoxyphenyl }-5,6,7,8-tetrahydronaphthalen-2-ol; osteoporosis; breast cancer | EISAI CO., LTD. (JP) | 2006-06-01 | — | — | US | disclosed |
| EP-1577288-A1 | SELECTIVE ESTROGEN RECEPTOR MODULATORS | Eisai Co., Ltd. (JP) | 2005-09-21 | — | — | EP | disclosed |
| US-20050203079-A1 | Compounds having affinity at 5ht2C receptor and use thereof in therapy | GLAXO GROUP LIMITED | 2005-09-15 | — | — | US | disclosed |
| EP-1497265-A1 | COMPOUNDS HAVING AFFINITY AT 5HT2C RECEPTOR AND USE THEREOF IN THERAPY | GLAXO GROUP LIMITED (GB) | 2005-01-19 | — | — | EP | disclosed |
| WO-2003089409-A1 | COMPOUNDS HAVING AFFINITY AT 5HT2C RECEPTOR AND USE THEREOF IN THERAPY | GLAXO GROUP LIMITED (GB) | 2003-10-30 | — | — | WO | disclosed |
| US-4099954-A | Amide phosphorothiolate herbicides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1978-07-11 | — | — | US | disclosed |
| US-3998808-A | INSECTICIDES, FUNGICIDES | VELSICOL CHEMICAL CORPORATION (US) | 1976-12-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250368608-A1 | SELECTIVE HDAC6 INHIBITOR | HDAC6, HDAC3, HDAC1 | ALDH1A1 3394/4885NPC1 474/4885LMNA 4049/4885 |
| US-20050203079-A1 | Compounds having affinity at 5ht2C receptor and use thereof in therapy | HTR7, HTR2C, HTR3C | ALDH1A1 1439/4885NPC1 636/4885LMNA 1603/4885 |
| US-20090270412-A1 | PYRIDO[3,4-B]INDOLES AND METHODS OF USE | HTR3B, HTR4, HTR2C | ALDH1A1 1514/4885NPC1 3670/4885LMNA 4568/4885 |
| US-20200308145-A1 | BENZIMIDAZOLE DERIVATIVES AND THEIR USES | TRPC6, TRPV6, TRPM6 | ALDH1A1 1564/4885NPC1 1035/4885LMNA 4022/4885 |
| US-20060116364-A1 | Such as (R)-6-{2-{ethyl[4-(2-ethylaminoethyl)benzyl]amino }-4-methoxyphenyl }-5,6,7,8-tetrahydronaphthalen-2-ol; osteoporosis; breast cancer | BRCA1, BCR, RCC1 | ALDH1A1 2275/4885NPC1 2132/4885LMNA 1494/4885 |
| US-11332459-B2 | Benzimidazole derivatives and their uses | TRPC6, TRPV6, TRPM6 | ALDH1A1 1564/4885NPC1 1035/4885LMNA 4022/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.