Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
| ▸ | OGA | O60502 | 2/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2901841 | 0.87 | VCP (0.43) | OGA | |
| SCHEMBL2901839 | 0.87 | VCP (0.43) | OGA | |
| SCHEMBL5820433 | 0.82 | — | — | |
| SCHEMBL2901836 | 0.81 | PDE4D (0.37) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL2908190 | 0.75 | PDE4D (0.42) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL4140487 | 0.74 | PDE4D (0.39) | FFAR4PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL2901989 | 0.73 | PDE4D (0.42) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL2908807 | 0.72 | PDE4D (0.37) | PDE4APDE4BPDE4CPDE4DCHRM2 | |
| SCHEMBL2909161 | 0.72 | PDE4D (0.33) | FFAR4PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL4136062 | 0.72 | PDE4D (0.37) | PDE4APDE4BPDE4CPDE4DCHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1692109-A2 | PHOSPHODIESTERASE 4 INHIBITORS, INCLUDING N-SUBSTITUTED DIARYLAMINE ANALOGS | Memory Pharmaceuticals Corporation (US) | 2006-08-23 | — | — | EP | disclosed |
| WO-2005061458-A2 | PHOSPHODIESTERASE 4 INHIBITORS, INCLUDING N-SUBSTITUTED DIARYLAMINE ANALOGS | MEMORY PHARMACEUTICALS CORPORATION (US) | 2005-07-07 | — | — | WO | disclosed |