SCHEMBL5820458

SCHEMBL5820458

COC1=CC(=O)c2c(OC)ccc(OC)c2C1=O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.53
KDM4E B2RXH2 3/20 0.53
HTT P42858 2/20 0.53
MAPK1 P28482 2/20 0.53
HKDC1 Q2TB90 2/20 0.53
S1PR4 O95977 1/20 0.53
HSP90AA1 P07900 1/20 0.53
G6PD P11413 1/20 0.53
S1PR1 P21453 1/20 0.53
OPRK1 P41145 1/20 0.53
RAB9A P51151 1/20 0.53
CACNA1B Q00975 1/20 0.53
APBA1 Q02410 1/20 0.53
MCL1 Q07820 1/20 0.53
NPSR1 Q6W5P4 1/20 0.53
APOBEC3G Q9HC16 1/20 0.53
TLR9 Q9NR96 1/20 0.53
ALDH1A1 P00352 2/20 0.52
MEN1 O00255 2/20 0.52
USP2 O75604 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30004035 1.00 MAPT (0.53) MAPTKDM4EHTTMAPK1HKDC1
SCHEMBL23271796 0.80 MAPT (0.64) MAPTKDM4EHTTMAPK1S1PR4
SCHEMBL30003449 0.80 MAPT (0.64) MAPTKDM4EHTTMAPK1S1PR4
SCHEMBL14662840 0.78 MAPT (0.62) MAPTKDM4EHTTMAPK1S1PR4
SCHEMBL30003483 0.78 MAPT (0.62) MAPTKDM4EHTTMAPK1S1PR4
SCHEMBL23271773 0.78 MAPT (0.52) MAPTKDM4EHTTMAPK1S1PR4
SCHEMBL15745741 0.78 MAPT (0.55) MAPTKDM4EHTTMAPK1S1PR4
SCHEMBL9176608 0.78 MAPT (0.52) MAPTKDM4EHTTMAPK1S1PR4
SCHEMBL30003138 0.78 MAPT (0.52) MAPTKDM4EHTTMAPK1S1PR4
SCHEMBL30002739 0.78 MAPT (0.52) MAPTKDM4EHTTMAPK1S1PR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1827578-A Anti-tumor naphthoquinone formic acid soft analogues UNIV SHANGHAI JIAOTONG (CN) 2006-09-06 CN claimed
US-11613509-B2 Radical polymerization control agent and radical polymerization control method KAWASAKI KASEI CHEMICALS LTD. (JP) 2023-03-28 US disclosed
CN-110891980-B Radical polymerization control agent and radical polymerization control method 川崎化成工业株式会社 2022-09-30 CN disclosed
US-20210122692-A1 RADICAL POLYMERIZATION CONTROL AGENT AND RADICAL POLYMERIZATION CONTROL METHOD KAWASAKI KASEI CHEMICALS LTD. (JP) 2021-04-29 US disclosed
CN-110891980-A Radical polymerization control agent and radical polymerization control method 川崎化成工业株式会社 2020-03-17 CN disclosed
WO-2006107827-A1 SKIN BONDING PROCESS CREIGHTON UNIVERSITY (US) 2006-10-12 WO disclosed
CN-1827578-A Anti-tumor naphthoquinone formic acid soft analogues UNIV SHANGHAI JIAOTONG (CN) 2006-09-06 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11613509-B2 Radical polymerization control agent and radical polymerization control method PPOX, NOX4, CROCC MAPT 188/4885KDM4E 1028/4885HTT 1452/4885
US-20210122692-A1 RADICAL POLYMERIZATION CONTROL AGENT AND RADICAL POLYMERIZATION CONTROL METHOD PPOX, NOX4, CROCC MAPT 188/4885KDM4E 1028/4885HTT 1452/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.