SCHEMBL5820549

SCHEMBL5820549

CC(C)(C)C1=CCC([Si](C)(C)c2c(C(C)(C)C)cc(-c3ccccc3)c3c2Cc2cc(C(C)(C)C)ccc2-3)=C1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6385816 0.82
SCHEMBL5820550 0.69 CYP19A1 (0.33)
SCHEMBL4486310 0.69 NPC1 (0.42)
Hydrochloric Acid SCHEMBL6385290 0.68 CYP19A1 (0.32)
SCHEMBL27989925 0.66 NPC1 (0.40)
SCHEMBL8397303 0.65
SCHEMBL27558991 0.63 CYP1A2 (0.31)
SCHEMBL5011498 0.63
Hydrochloric Acid SCHEMBL3149077 0.63
SCHEMBL4557939 0.62 NPC1 (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2006137818-A1 CATALYST COMPONENTS AND THEIR USE IN THE POLYMERIZATION OF OLEFINS FINA TECHNOLOGY, INC. (US) 2006-12-28 WO disclosed
US-20050148460-A1 Catalyst components and their use in the polymerization of olefins FINA TECHNOLOGY, INC. 2005-07-07 US disclosed