Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5820550 | 0.98 | CYP19A1 (0.33) | CYP19A1 | |
| Hydrochloric Acid SCHEMBL6386343 | 0.81 | — | — | |
| SCHEMBL6385818 | 0.79 | NPC1 (0.30) | CYP19A1 | |
| SCHEMBL7542664 | 0.73 | GPR3 (0.33) | — | |
| SCHEMBL5820549 | 0.68 | — | — | |
| SCHEMBL8397304 | 0.65 | NPC1 (0.31) | — | |
| SCHEMBL6693816 | 0.63 | NPC1 (0.33) | CYP19A1 | |
| SCHEMBL26004981 | 0.62 | ALDH1A1 (0.57) | CYP19A1 | |
| SCHEMBL5546203 | 0.62 | ALDH1A1 (0.57) | CYP19A1 | |
| SCHEMBL4486310 | 0.61 | NPC1 (0.42) | CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050148460-A1 | Catalyst components and their use in the polymerization of olefins | FINA TECHNOLOGY, INC. | 2005-07-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050148460-A1 | Catalyst components and their use in the polymerization of olefins | NPY5R, SSTR5, FGR | CYP19A1 165/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.