SCHEMBL582057

SCHEMBL582057

C=CC[Ru]CC=C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Carbon Monoxide SCHEMBL6551100 0.89
SCHEMBL3344252 0.80 ALDH1A1 (0.33)
SCHEMBL5692933 0.70
SCHEMBL28907156 0.60
SCHEMBL7567427 0.60
Allylamine SCHEMBL4557242 0.57
SCHEMBL10586271 0.57
SCHEMBL3992 0.57
SCHEMBL474594 0.57
SCHEMBL9312342 0.57

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2417139-B1 PREPARATION OF SATURATED KETONE MORPHINAN COMPOUNDS BY CATALYTIC ISOMERIZATION MALLINCKRODT LLC (US) 2016-03-23 EP claimed
EP-2563793-B1 PREPARATION OF SATURATED KETONE MORPHINAN COMPOUNDS HAVING LOW METAL CONTENT MALLINCKRODT LLC (US) 2014-10-22 EP claimed
US-8563725-B2 Preparation of saturated ketone morphinan compounds having low metal content MALLINCKRODT LLC (US) 2013-10-22 US claimed
EP-2563793-A1 PREPARATION OF SATURATED KETONE MORPHINAN COMPOUNDS HAVING LOW METAL CONTENT Mallinckrodt LLC (US) 2013-03-06 EP claimed
US-8293907-B2 Preparation of saturated ketone morphinan compounds by catalytic isomerization MALLINCKRODT INC. (US) 2012-10-23 US claimed
EP-2417139-A1 PREPARATION OF SATURATED KETONE MORPHINAN COMPOUNDS BY CATALYTIC ISOMERIZATION Mallinckrodt LLC (US) 2012-02-15 EP claimed
US-20110269963-A1 Preparation of Saturated Ketone Morphinan Compounds Having Low Metal Content MALLINCKRODT INC. (US) 2011-11-03 US claimed
WO-2011137086-A1 PREPARATION OF SATURATED KETONE MORPHINAN COMPOUNDS HAVING LOW METAL CONTENT MALLINCKRODT LLC (US) 2011-11-03 WO claimed
US-20100261904-A1 Preparation of Saturated Ketone Morphinan Compounds by Catalytic Isomerization MALLINCKRODT INC. (US) 2010-10-14 US claimed
WO-2010118271-A1 PREPARATION OF SATURATED KETONE MORPHINAN COMPOUNDS BY CATALYTIC ISOMERIZATION MALLINCKRODT INC. (US) 2010-10-14 WO claimed
US-11282745-B2 Methods for filling features with ruthenium APPLIED MATERIALS, INC. (US) 2022-03-22 US disclosed
CN-105017053-B Synthesis method of salicylamide 合肥祥晨化工有限公司 2016-11-16 CN disclosed
CN-105017053-A Synthesis method of salicylamide HEFEI XIANGCHEN CHEMICAL CO LTD 2015-11-04 CN disclosed
EP-2563793-B1 PREPARATION OF SATURATED KETONE MORPHINAN COMPOUNDS HAVING LOW METAL CONTENT MALLINCKRODT LLC (US) 2014-10-22 EP disclosed
CN-102807504-B Method for synthesizing salicylamide LUO MEI 2014-01-15 CN disclosed
US-6590048-B1 Catalysts comprising group VIII compounds used for cyclization of crown ethers, antibiotics, veterinary medicines or perfumes STUDIENGESELLSCHAFT KOHLE MBH (DE) 2003-07-08 US disclosed
EP-1037897-B1 HIGHLY ACTIVE CATIONIC RUTHENIUM AND OSMIUM COMPLEXES FOR OLEFIN METATHESIS REACTIONS STUDIENGESELLSCHAFT KOHLE MBH (DE) 2002-06-12 EP disclosed
EP-1037897-A1 HIGHLY ACTIVE CATIONIC RUTHENIUM AND OSMIUM COMPLEXES FOR OLEFIN METATHESIS REACTIONS Studiengesellschaft Kohle mbH (DE) 2000-09-27 EP disclosed
WO-1999028330-A1 HIGHLY ACTIVE CATIONIC RUTHENIUM AND OSMIUM COMPLEXES FOR OLEFIN METATHESIS REACTIONS STUDIENGESELLSCHAFT KOHLE MBH (DE) 1999-06-10 WO disclosed
EP-0921129-A1 Highly active cationic ruthenium and osmium complexes for olefin metathesis reactions Studiengesellschaft Kohle mbH (DE) 1999-06-09 EP disclosed