Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 15/20 | 0.54 |
| ▸ | ITGAV | P06756 | 15/20 | 0.54 |
| ▸ | ITGB5 | P18084 | 6/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5809683 | 0.86 | ITGB3 (0.66) | ITGB3ITGAVITGB5 | |
| SCHEMBL861676 | 0.83 | ITGB3 (0.56) | ITGB3ITGAVITGB5 | |
| SCHEMBL5815728 | 0.81 | ITGB3 (0.81) | ITGB3ITGAVITGB5 | |
| SCHEMBL861296 | 0.80 | ITGB3 (0.58) | ITGB3ITGAVITGB5 | |
| SCHEMBL861561 | 0.79 | ITGB3 (0.52) | ITGB3ITGAVITGB5 | |
| SCHEMBL861581 | 0.78 | ITGB3 (0.58) | ITGB3ITGAVITGB5 | |
| SCHEMBL860336 | 0.78 | ITGB3 (0.59) | ITGB3ITGAVITGB5 | |
| SCHEMBL861506 | 0.78 | ITGB3 (0.51) | ITGB3ITGAVITGB5 | |
| SCHEMBL862008 | 0.78 | ITGB3 (0.57) | ITGB3ITGAVITGB5 | |
| SCHEMBL860404 | 0.77 | ITGB3 (0.57) | ITGB3ITGAVITGB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006108040-A1 | SUBSTITUTED INDOLES AND THEIR USE AS INTEGRIN ANTAGONISTS | JANSSEN PHARMACEUTICA, N.V. (BE) | 2006-10-12 | — | — | WO | disclosed |
| WO-2006072353-A1 | AZETIDINE-SUBSTITUTED PYRAZOLINES AS PAR-1 ANTAGONISTS | BAYER HEALTHCARE AG (DE) | 2006-07-13 | — | — | WO | disclosed |