Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 20/20 | 0.66 |
| ▸ | ITGAV | P06756 | 20/20 | 0.66 |
| ▸ | ITGB5 | P18084 | 6/20 | 0.66 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5820830 | 0.86 | ITGB3 (0.54) | ITGB3ITGAVITGB5 | |
| SCHEMBL3676698 | 0.80 | ITGB3 (1.00) | ITGB3ITGAVITGB5ITGA2B | |
| SCHEMBL5810721 | 0.79 | ITGB3 (0.73) | ITGB3ITGAVITGB5ITGA2B | |
| SCHEMBL861262 | 0.77 | ITGB3 (0.60) | ITGB3ITGAVITGB5 | |
| SCHEMBL20153715 | 0.73 | ITGAV (0.39) | ITGB3ITGAVITGB5ITGA2B | |
| SCHEMBL5809659 | 0.73 | ITGB3 (1.00) | ITGB3ITGAVITGB5 | |
| SCHEMBL29390935 | 0.71 | MPO (0.39) | ITGB3ITGAV | |
| SCHEMBL3138861 | 0.71 | MPO (0.39) | ITGB3ITGAV | |
| SCHEMBL16607425 | 0.69 | ITGAV (0.40) | ITGB3ITGAVITGA2B | |
| SCHEMBL29702182 | 0.69 | ITGAV (0.40) | ITGB3ITGAVITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006108040-A1 | SUBSTITUTED INDOLES AND THEIR USE AS INTEGRIN ANTAGONISTS | JANSSEN PHARMACEUTICA, N.V. (BE) | 2006-10-12 | — | — | WO | disclosed |