Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 14/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | AURKA | O14965 | 1/20 | 0.37 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.37 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.37 |
| ▸ | BTK | Q06187 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30834121 | 0.72 | HRH4 (0.41) | HRH4LMNA | |
| SCHEMBL27201412 | 0.72 | HRH4 (0.41) | HRH4LMNA | |
| SCHEMBL27201344 | 0.69 | NUDT1 (0.53) | HRH4 | |
| SCHEMBL30885265 | 0.69 | NUDT1 (0.53) | HRH4 | |
| SCHEMBL1317810 | 0.67 | AURKA (0.63) | KMT2ALMNAAURKAPDPK1AURKB | |
| SCHEMBL3720386 | 0.67 | AURKA (0.63) | KMT2ALMNAAURKAPDPK1AURKB | |
| SCHEMBL16977369 | 0.67 | AURKA (0.63) | LMNAAURKAPDPK1AURKBBTK | |
| SCHEMBL12118769 | 0.67 | AURKA (0.63) | LMNAAURKAPDPK1AURKBBTK | |
| SCHEMBL1318722 | 0.67 | AURKA (0.63) | KMT2ALMNAAURKAPDPK1AURKB | |
| SCHEMBL1317503 | 0.67 | PDPK1 (0.61) | LMNAAURKAPDPK1AURKBBTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006135383-A2 | INDAZOLES | MYRIAD GENETICS, INC. (US) | 2006-12-21 | — | — | WO | disclosed |