Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA3 | P07451 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA6 | P23280 | 1/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14308974 | 0.93 | LMNA (0.46) | LMNAKMT2AHTTCA12CA1 | |
| SCHEMBL4733611 | 0.83 | LMNA (0.47) | LMNAKMT2AHTTMEN1CYP1A2 | |
| SCHEMBL21570830 | 0.82 | LMNA (0.50) | LMNAKMT2ACA12CA1CA2 | |
| SCHEMBL5871771 | 0.80 | NAMPT (0.47) | LMNA | |
| SCHEMBL9371529 | 0.79 | LMNA (0.55) | LMNAKMT2AHTTCA12CA1 | |
| SCHEMBL17595784 | 0.79 | LMNA (0.50) | LMNAKMT2AHTTCA12CA1 | |
| SCHEMBL5148311 | 0.79 | LMNA (0.53) | LMNAKMT2ACA12CA1CA2 | |
| SCHEMBL16436869 | 0.78 | HTT (0.45) | LMNAKMT2AHTTMEN1CYP1A2 | |
| SCHEMBL11816203 | 0.77 | HTT (0.44) | LMNAKMT2AHTTMEN1CYP1A2 | |
| SCHEMBL4846362 | 0.77 | LMNA (0.45) | LMNAKMT2AKDM4EMEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006127300-A1 | SYNTHESIS OF (S)-α-ETHYL-2-OXO-1-PYRROLIDINEACETAMIDE | CAMBREX CHARLES CITY, INC. (US) | 2006-11-30 | — | — | WO | disclosed |