SCHEMBL5871771

SCHEMBL5871771

CCCCCCCCNC(=O)N1CCCC1=O

nearest known ligand 0.47

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
NAMPT P43490 2/20 0.47
ASAH1 Q13510 1/20 0.47
LMNA P02545 1/20 0.45
EPHX1 P07099 4/20 0.44
ADRB2 P07550 1/20 0.42
ADRB1 P08588 1/20 0.42
ADRB3 P13945 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16381786 0.94 KDM4E (0.45) NAMPTASAH1EPHX1
SCHEMBL5492822 0.94 KDM4E (0.45) NAMPTASAH1EPHX1
SCHEMBL9158519 0.94 KDM4E (0.45) NAMPTASAH1EPHX1
SCHEMBL4733611 0.94 LMNA (0.47) LMNA
SCHEMBL16151989 0.93 KDM4E (0.43) NAMPTASAH1LMNAEPHX1
SCHEMBL10374083 0.91 NAMPT (0.49) NAMPTASAH1EPHX1ADRB2ADRB1
SCHEMBL16436869 0.89 HTT (0.45) LMNA
SCHEMBL11816203 0.88 HTT (0.44) LMNA
SCHEMBL18012879 0.86 LMNA (0.44) NAMPTASAH1LMNA
SCHEMBL5019491 0.86 LMNA (0.44) NAMPTASAH1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6991744-B2 Refrigerant compositions containing a compatibilizer E. I. DU PONT DE NEMOURS AND COMPANY (US) 2006-01-31 US disclosed
US-6962665-B2 Refrigerant compositions containing a compatibilizer E. I. DU PONT DE NEMOURS AND COMPANY (US) 2005-11-08 US disclosed
US-20040222402-A1 Refrigerant compositions containing a compatibilizer MINOR BARBARA HAVILAND (US) 2004-11-11 US disclosed
EP-1451263-A1 REFRIGERANT COMPOSITIONS CONTAINING A COMPATIBILIZER AND USE THEREOF IN A COMPRESSION REFRIGERATION APPARATUS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2004-09-01 EP disclosed
WO-2002046328-A9 REFRIGERANT COMPOSITIONS CONTAINING A COMPATIBILIZER DU PONT (US) 2004-03-04 WO disclosed
US-20030209688-A1 Refrigerant compositions containing a compatibilizer E. I. DU PONT DE NEMOURS AND COMPANY 2003-11-13 US disclosed
EP-1341868-A2 REFRIGERANT COMPOSITIONS CONTAINING A COMPATIBILIZER E.I. DU PONT DE NEMOURS AND COMPANY (US) 2003-09-10 EP disclosed
WO-2003050200-A1 REFRIGERANT COMPOSITIONS CONTAINING A COMPATIBILIZER AND USE THEROF IN A COMPRESSION REFRIGERATION APPARATUS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2003-06-19 WO disclosed
US-20030034477-A1 Refrigerant compositions containing a compatibilizer E. I. DU PONT DE NEMOURS AND COMPANY 2003-02-20 US disclosed
WO-2002046328-A2 REFRIGERANT COMPOSITIONS CONTAINING A COMPATIBILIZER E.I. DU PONT DE NEMOURS AND COMPANY (US) 2002-06-13 WO disclosed