Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 1/20 | 0.56 |
| ▸ | FNTB | P49356 | 1/20 | 0.56 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.50 |
| ▸ | MMP8 | P22894 | 1/20 | 0.47 |
| ▸ | RRM1 | P23921 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.45 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.44 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.44 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.43 |
| ▸ | NAAA | Q02083 | 2/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1489369 | 0.85 | FNTA (0.66) | FNTAFNTBDPP7MMP8RRM1 | |
| SCHEMBL10769018 | 0.81 | MMP8 (0.51) | FNTAFNTBDPP7MMP8RRM1 | |
| SCHEMBL1258601 | 0.80 | GNAI3 (0.56) | FNTAFNTBDPP7MMP8RRM1 | |
| SCHEMBL25405485 | 0.79 | HDAC7 (0.56) | FNTAFNTBDPP7RRM1EPHX1 | |
| SCHEMBL18542819 | 0.78 | DPP7 (0.49) | FNTAFNTBDPP7MMP8RRM1 | |
| SCHEMBL20503323 | 0.78 | FNTA (0.68) | FNTAFNTBDPP7MMP8RRM1 | |
| SCHEMBL17070909 | 0.78 | DPP7 (0.53) | FNTAFNTBDPP7MMP8RRM1 | |
| SCHEMBL27991817 | 0.78 | FNTA (0.49) | FNTAFNTBDPP7MMP8RRM1 | |
| SCHEMBL6943898 | 0.78 | DPP7 (0.52) | DPP7RRM1EPHX1GNAI3GNAO1 | |
| SCHEMBL9462370 | 0.78 | DPP7 (0.52) | DPP7MMP8RRM1EPHX1GNAI3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006113606-A2 | HISTONE DEACETYLASE INHIBITORS | JOHNS HOPKINS UNIVERSITY (US) | 2006-10-26 | — | — | WO | disclosed |