Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | PLAU | P00749 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.33 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1804931 | 0.72 | TDP1 (0.46) | CA12CA9ALDH1A1SMN1; SMN2GAA | |
| SCHEMBL6277865 | 0.68 | ALDH1A1 (0.38) | CA12CA9ALDH1A1GAATDP1 | |
| SCHEMBL29460268 | 0.67 | TDP1 (0.50) | CA12CA9ALDH1A1SMN1; SMN2GAA | |
| SCHEMBL5821395 | 0.67 | MAPT (0.45) | CA12CA9ALDH1A1SMN1; SMN2GAA | |
| SCHEMBL17711573 | 0.67 | HDAC8 (0.43) | ALDH1A1SMN1; SMN2TDP1HDAC3HDAC4 | |
| SCHEMBL5821388 | 0.66 | MAPT (0.44) | CA12CA9ALDH1A1SMN1; SMN2GAA | |
| SCHEMBL14935761 | 0.63 | CA12 (0.47) | CA12CA9ALDH1A1SMN1; SMN2GAA | |
| SCHEMBL2029095 | 0.63 | CA12 (0.47) | CA12CA9ALDH1A1SMN1; SMN2GAA | |
| SCHEMBL28536149 | 0.63 | CA12 (0.42) | CA12CA9ALDH1A1SMN1; SMN2GAA | |
| SCHEMBL2020475 | 0.63 | TDP1 (0.55) | CA12CA9ALDH1A1SMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006050471-A2 | ACYLOXYALKYL CARBAMATE PRODRUGS OF SULFINIC ACIDS, METHODS OF SYNTHESIS, AND USE | XENOPORT, INC. (US) | 2006-05-11 | — | — | WO | disclosed |