Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRG2 | P18507 | 20/20 | 0.64 |
| ▸ | GABRB3 | P28472 | 20/20 | 0.64 |
| ▸ | GABRA5 | P31644 | 20/20 | 0.64 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.43 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.43 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3871909 | 0.89 | GABRG2 (0.68) | GABRG2GABRB3GABRA5GABRA1GABRA3 | |
| SCHEMBL3871685 | 0.78 | GABRG2 (0.77) | GABRG2GABRB3GABRA5GABRA1GABRA3 | |
| SCHEMBL3574029 | 0.78 | GABRG2 (1.00) | GABRG2GABRB3GABRA5GABRA1GABRA3 | |
| SCHEMBL4935173 | 0.76 | GABRG2 (0.51) | GABRG2GABRB3GABRA5 | |
| SCHEMBL3870304 | 0.76 | GABRG2 (0.74) | GABRG2GABRB3GABRA5GABRA1GABRA3 | |
| SCHEMBL3879446 | 0.76 | GABRG2 (0.62) | GABRG2GABRB3GABRA5GABRA1GABRA3 | |
| SCHEMBL5894375 | 0.76 | GABRG2 (0.67) | GABRG2GABRB3GABRA5GABRA1GABRA3 | |
| SCHEMBL3871728 | 0.74 | GABRG2 (0.71) | GABRG2GABRB3GABRA5GABRA1GABRA3 | |
| SCHEMBL3878085 | 0.71 | GABRG2 (0.67) | GABRG2GABRB3GABRA5GABRA1GABRA3 | |
| SCHEMBL3871679 | 0.71 | GABRG2 (1.00) | GABRG2GABRB3GABRA5GABRA1GABRA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006040038-A1 | IMIDAZO [1, 5-A]TRIAZOLO[1, 5-D]BENZODIAZEPINE DERIVATIVES FOR THE TREATMENT OF COGNITIVE DISORDERS | F.HOFFMANN-LA ROCHE AG (CH) | 2006-04-20 | — | — | WO | claimed |