Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 9/20 | 0.54 |
| ▸ | GBA1 | P04062 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | NPY2R | P49146 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5816127 | 0.97 | SCD (0.52) | SCDGBA1KMT2ANPY2RMEN1 | |
| SCHEMBL5821745 | 0.89 | SCD (0.42) | SCDKMT2AMEN1MAPK1TSHR | |
| SCHEMBL5822108 | 0.87 | SCD (0.55) | SCDGBA1KMT2ANPY2RMEN1 | |
| SCHEMBL5818472 | 0.87 | SCD (0.58) | SCDGBA1 | |
| SCHEMBL5821754 | 0.86 | SCD (0.53) | SCDGBA1LMNA | |
| SCHEMBL5821535 | 0.86 | SCD (0.42) | SCDKMT2AMEN1MAPK1LMNA | |
| SCHEMBL5821234 | 0.86 | SCD (0.58) | SCDGBA1 | |
| SCHEMBL5821508 | 0.86 | SCD (0.49) | SCDGBA1KMT2ANPY2RMEN1 | |
| SCHEMBL5821805 | 0.85 | SCD (0.51) | SCDGBA1KMT2AMEN1 | |
| SCHEMBL5816785 | 0.84 | SCD (0.57) | SCDGBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006125180-A1 | PIPERAZINE DERIVATIVES AND THEIR USES AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC. (CA) | 2006-11-23 | — | — | WO | disclosed |