Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.40 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | JAK3 | P52333 | 3/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5821535 | 0.97 | SCD (0.42) | SCDKMT2AMEN1MAPK1ALDH1A1 | |
| SCHEMBL5821701 | 0.89 | SCD (0.54) | SCDKMT2AMEN1MAPK1TSHR | |
| SCHEMBL5816171 | 0.87 | SCD (0.47) | SCDKMT2AMEN1MAPK1ALDH1A1 | |
| SCHEMBL5816372 | 0.87 | SCD (0.45) | SCDHCRTR1HCRTR2HTTSMN1; SMN2 | |
| SCHEMBL5816199 | 0.86 | SCD (0.51) | SCDKMT2AMEN1MAPK1ALDH1A1 | |
| SCHEMBL5816127 | 0.86 | SCD (0.52) | SCDKMT2AMEN1MAPK1TSHR | |
| SCHEMBL5821544 | 0.85 | DRD2 (0.43) | SCDKMT2AMEN1MAPK1SLC6A9 | |
| SCHEMBL5822072 | 0.85 | SCD (0.49) | SCDKMT2AMEN1MAPK1MAPT | |
| SCHEMBL5821224 | 0.84 | SCD (0.46) | SCDKMT2AMEN1MAPK1ALDH1A1 | |
| SCHEMBL5816215 | 0.83 | HTT (0.48) | SCDKMT2AMEN1MAPK1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006125180-A1 | PIPERAZINE DERIVATIVES AND THEIR USES AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC. (CA) | 2006-11-23 | — | — | WO | disclosed |