Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 10/20 | 0.55 |
| ▸ | GBA1 | P04062 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | NPY2R | P49146 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5816127 | 0.88 | SCD (0.52) | SCDGBA1MEN1KMT2ANPY2R | |
| SCHEMBL5821701 | 0.87 | SCD (0.54) | SCDGBA1MEN1KMT2ANPY2R | |
| SCHEMBL5821508 | 0.86 | SCD (0.49) | SCDGBA1MEN1KMT2ANPY2R | |
| SCHEMBL5821234 | 0.86 | SCD (0.58) | SCDGBA1 | |
| SCHEMBL5818660 | 0.85 | SCD (0.53) | SCDGBA1MEN1KMT2ANPY2R | |
| SCHEMBL5816957 | 0.84 | SCD (0.55) | SCDGBA1MEN1KMT2A | |
| SCHEMBL5822275 | 0.81 | SCD (0.52) | SCDGBA1MEN1KMT2AMAPK1 | |
| SCHEMBL5821442 | 0.80 | MAPK1 (0.55) | SCDGBA1MEN1KMT2AMAPK1 | |
| SCHEMBL5821751 | 0.79 | MGLL (0.51) | SCDGBA1MEN1KMT2ANPY2R | |
| SCHEMBL5820078 | 0.79 | SCD (0.52) | SCDGBA1MEN1KMT2ANPY2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006125180-A1 | PIPERAZINE DERIVATIVES AND THEIR USES AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC. (CA) | 2006-11-23 | — | — | WO | disclosed |