Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 5/20 | 0.34 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | AGXT | P21549 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5812081 | 0.78 | IDO1 (0.34) | IDO1LOXL2TAAR1AGXT | |
| SCHEMBL5030489 | 0.69 | PLA2G1B (0.33) | TAAR1 | |
| SCHEMBL2298642 | 0.65 | STAT3 (0.43) | — | |
| SCHEMBL5871483 | 0.63 | TAAR1 (0.45) | IDO1LOXL2TAAR1 | |
| SCHEMBL1983107 | 0.63 | CHRNA7 (0.61) | IDO1LOXL2TAAR1 | |
| SCHEMBL2098314 | 0.62 | KDM4E (0.56) | — | |
| SCHEMBL11846749 | 0.61 | HIF1A (0.41) | IDO1LOXL2 | |
| SCHEMBL15692139 | 0.60 | LMNA (0.37) | IDO1LOXL2TAAR1AGXT | |
| SCHEMBL894461 | 0.59 | IDO1 (0.34) | IDO1LOXL2TAAR1AGXT | |
| SCHEMBL18872639 | 0.59 | ALDH1A1 (0.37) | LOXL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006086609-A2 | INHIBITORS OF TRYPTASE | AXYS PHARMACEUTICALS, INC. (US) | 2006-08-17 | — | — | WO | disclosed |