Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.43 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PARK7 | Q99497 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5816189 | 0.91 | SCD (0.46) | SCDMEN1KMT2AADRA1DADRA1A | |
| SCHEMBL5821234 | 0.91 | SCD (0.58) | SCDADRA1DADRA1AADRA1BHSD17B10 | |
| SCHEMBL5821470 | 0.88 | SCD (0.48) | SCDMEN1KMT2AGFERPARK7 | |
| SCHEMBL5821535 | 0.86 | SCD (0.42) | SCDMEN1KMT2AMAPK1USP2 | |
| SCHEMBL5816199 | 0.86 | SCD (0.51) | SCDMEN1KMT2AMAPK1USP2 | |
| SCHEMBL5821163 | 0.85 | SCD (0.47) | SCDMEN1KMT2AGFERMAPK1 | |
| SCHEMBL5818649 | 0.85 | L3MBTL1 (0.48) | SCDMEN1KMT2AMAPK1USP2 | |
| SCHEMBL5821745 | 0.85 | SCD (0.42) | SCDMEN1KMT2AMAPK1USP2 | |
| SCHEMBL5816215 | 0.82 | HTT (0.48) | SCDMEN1KMT2AMAPK1USP2 | |
| SCHEMBL5816957 | 0.82 | SCD (0.55) | SCDMEN1KMT2AADRA1DADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006125180-A1 | PIPERAZINE DERIVATIVES AND THEIR USES AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC. (CA) | 2006-11-23 | — | — | WO | disclosed |