⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3282197 | 0.81 | — | — | |
| SCHEMBL10889704 | 0.81 | — | — | |
| SCHEMBL7342627 | 0.81 | — | — | |
| SCHEMBL12129341 | 0.81 | — | — | |
| SCHEMBL3371401 | 0.81 | — | — | |
| SCHEMBL24326412 | 0.81 | — | — | |
| SCHEMBL14713117 | 0.79 | TRPV1 (0.48) | — | |
| SCHEMBL14713034 | 0.79 | TRPV1 (0.48) | — | |
| SCHEMBL28709184 | 0.77 | ALDH1A1 (0.43) | — | |
| SCHEMBL2806516 | 0.75 | TRPV1 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2006206597-A | METHOD FOR PRODUCING SUBSTITUTED 2,5-DIAMINO-3-HYDROXYHEXANE | ABBOTT LAB | 2006-08-10 | — | — | JP | disclosed |
| EP-1007517-B1 | PROCESS FOR THE PREPARATION OF 5-HYDROXYMETHYLTHIAZOLES | ABBOTT LAB (US) | 2003-10-08 | — | — | EP | disclosed |
| EP-0916646-B1 | Process for the preparation of a substituted 2,5-diamino-3-hydroxyhexane | ABBOTT LAB (US) | 2003-05-02 | — | — | EP | disclosed |
| EP-0916646-B1 | Process for the preparation of a substituted 2,5-diamino-3-hydroxyhexane | ABBOTT LAB (US) | 2003-05-02 | — | — | EP | disclosed |
| EP-0984921-B1 | PROCESS FOR THE PREPARATION OF SUBSTITUTED KETO-ENAMINES | ABBOTT LAB (US) | 2002-09-18 | — | — | EP | disclosed |
| EP-0729941-B1 | Process for producing keto nitrile derivative and hexenone derivative | TAKASAGO PERFUMERY CO LTD (JP) | 2001-06-13 | — | — | EP | disclosed |
| EP-1007517-A1 | PROCESS FOR THE PREPARATION OF 5-HYDROXYMETHYLTHIAZOLES | Abbott Laboratories (US) | 2000-06-14 | — | — | EP | disclosed |
| EP-0984921-A1 | PROCESS FOR THE PREPARATION OF SUBSTITUTED KETO-ENAMINES | Abbott Laboratories (US) | 2000-03-15 | — | — | EP | disclosed |
| EP-0773921-B1 | PROCESS FOR THE PREPARATION OF A SUBSTITUTED 2.5-DIAMINO-3-HYDROXYHEXANE | ABBOTT LAB (US) | 1999-12-01 | — | — | EP | disclosed |
| US-5959118-A | Process for the preparation of 5-hydroxymethylthiazoles | ABBOTT LABORATORIES (US) | 1999-09-28 | — | — | US | disclosed |
| US-5541321-A | Process for the preparation of a substituted diaminoalcohol | ABBOTT LABORATORIES (US) | 1996-07-30 | — | — | US | disclosed |
| US-5541328-A | Process for the preparation of a substituted 2,5-diamino-3-hydroxyhexane | ABBOTT LABORATORIES (US) | 1996-07-30 | — | — | US | disclosed |
| US-5541328-A | Process for the preparation of a substituted 2,5-diamino-3-hydroxyhexane | ABBOTT LABORATORIES (US) | 1996-07-30 | — | — | US | disclosed |
| US-5508409-A | Process for the preparation of a substituted 2.5-diamino-3-hydroxyhexane | ABBOTT LABORATORIES (US) | 1996-04-16 | — | — | US | disclosed |
| US-5508409-A | Process for the preparation of a substituted 2.5-diamino-3-hydroxyhexane | ABBOTT LABORATORIES (US) | 1996-04-16 | — | — | US | disclosed |
| WO-1996004232-A1 | PROCESS FOR THE PREPARATION OF A SUBSTITUTED 2.5-DIAMINO-3-HYDROXYHEXANE | ABBOTT LABORATORIES (US) | 1996-02-15 | — | — | WO | disclosed |
| US-5491253-A | Process for the preparation of a substituted 2,5-diamino-3-hydroxyhexane | ABBOTT LABORATORIES (US) | 1996-02-13 | — | — | US | disclosed |
| US-5491253-A | Process for the preparation of a substituted 2,5-diamino-3-hydroxyhexane | ABBOTT LABORATORIES (US) | 1996-02-13 | — | — | US | disclosed |
| US-5436339-A | Process for the preparation of a substituted diaminoalcohol | ABBOTT LABORATORIES (US) | 1995-07-25 | — | — | US | disclosed |
| WO-1995011224-A1 | PROCESS FOR THE PREPARATION OF A SUBSTITUTED 2,5-DIAMINO-3-HYDROXYHEXANE | ABBOTT LABORATORIES (US) | 1995-04-27 | — | — | WO | disclosed |