Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT2B | Q92831 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 7/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | PTK2 | Q05397 | 2/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | JAK1 | P23458 | 1/20 | 0.39 |
| ▸ | TYK2 | P29597 | 1/20 | 0.39 |
| ▸ | JAK3 | P52333 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | CRHBP | P24387 | 2/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19922803 | 0.74 | KAT2B (0.45) | KAT2BLMNAMAPTCYP1A2CYP3A4 | |
| SCHEMBL5821682 | 0.73 | ALDH1A1 (0.46) | LMNAMAPTHTTJAK2JAK1 | |
| SCHEMBL5821680 | 0.73 | ALDH1A1 (0.46) | LMNAMAPTHTTJAK2JAK1 | |
| SCHEMBL19922716 | 0.72 | KAT2B (0.47) | KAT2BLMNAMAPTCYP1A2CYP3A4 | |
| SCHEMBL3127032 | 0.71 | KAT2B (0.46) | KAT2BLMNAMAPTCYP1A2CYP3A4 | |
| SCHEMBL19929612 | 0.70 | KAT2B (0.48) | KAT2BLMNAMAPTCYP1A2CYP3A4 | |
| SCHEMBL15555691 | 0.69 | FGFR1 (0.44) | PTK2JAK2JAK1TYK2JAK3 | |
| SCHEMBL15583203 | 0.69 | KDR (0.43) | CYP3A4CYP2C9CYP2C19PTK2JAK2 | |
| SCHEMBL1131511 | 0.67 | ALDH1A1 (0.62) | KAT2BLMNAMAPTCYP1A2CYP3A4 | |
| SCHEMBL5982382 | 0.66 | KAT2B (0.64) | KAT2BLMNAMAPTCYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006124731-A2 | COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS | IRM LLC (BM) | 2006-11-23 | — | — | WO | disclosed |