Benzamide

Benzamide

SCHEMBL5823348

CC(C)(N)C(O)COc1ccccc1.NC(=O)c1ccccc1

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
PARP10 Q53GL7 7/20 0.53
LMNA P02545 1/20 0.46
MAPT P10636 2/20 0.46
TDP1 Q9NUW8 2/20 0.46
POLB P06746 1/20 0.46
CYP3A4 P08684 1/20 0.46
PARP1 P09874 1/20 0.46
TSHR P16473 1/20 0.46
CYP2C19 P33261 1/20 0.46
RECQL P46063 1/20 0.46
BLM P54132 1/20 0.46
PMP22 Q01453 1/20 0.46
HSD17B10 Q99714 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
CYP2D6 P10635 1/20 0.44
MTNR1A P48039 3/20 0.42
MTNR1B P49286 3/20 0.42
ABCB1 P08183 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21000898 0.88 LMNA (0.58) LMNACYP3A4TSHRCYP2C19HSD17B10
SCHEMBL4781079 0.87 MEN1 (0.57) PARP10LMNAMAPTTDP1TSHR
Benzamide SCHEMBL4775810 0.76 HIF1A (0.58) PARP10POLBABCB1
SCHEMBL29623022 0.74 LMNA (0.62) LMNAMAPTTSHRRECQLL3MBTL1
SCHEMBL11276637 0.74 LMNA (0.62) LMNAL3MBTL1CYP2D6MTNR1AMTNR1B
SCHEMBL6527642 0.74 PARP10 (0.54) PARP10LMNAMAPTPOLBTSHR
Benzamide SCHEMBL10641556 0.71 PPARA (0.72) PARP10MAPTTDP1POLBCYP3A4
Benzamide SCHEMBL11637930 0.71 MAPT (0.64) PARP10MAPTTDP1POLBCYP3A4
SCHEMBL28856430 0.71 PARP10 (0.65) PARP10MAPTTDP1POLBCYP3A4
SCHEMBL13295257 0.71 LMNA (0.45) LMNATDP1CYP2D6MTNR1AMTNR1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2006091464-A1 IMPROVED TIME/ TEMPERATURE INDICATORS SUN CHEMICAL CORPORATION (US) 2006-08-31 WO disclosed