Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 6/20 | 0.41 |
| ▸ | CCNT1 | O60563 | 5/20 | 0.39 |
| ▸ | CDK9 | P50750 | 5/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.37 |
| ▸ | F10 | P00742 | 1/20 | 0.37 |
| ▸ | PLAU | P00749 | 1/20 | 0.37 |
| ▸ | PLAT | P00750 | 1/20 | 0.37 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5822824 | 0.92 | CCNT1 (0.45) | KDM4EMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL5950685 | 0.89 | KDM4E (0.39) | KDM4EMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL5820234 | 0.85 | KDM4E (0.40) | KDM4EMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL5821981 | 0.81 | HTR1A (0.42) | KDM4EMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL5821626 | 0.81 | CCNT1 (0.42) | KDM4EMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL5821984 | 0.81 | HTR1A (0.42) | KDM4EMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL5816276 | 0.81 | KDM4E (0.50) | KDM4EMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL5824183 | 0.79 | CCNT1 (0.39) | KDM4EMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL5950590 | 0.75 | CDK9 (0.38) | KDM4EMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL5822413 | 0.75 | ABCB1 (0.52) | KDM4EMEN1ALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006113458-A1 | HETEROCYCLIC INHIBITORS OF PROTEIN ARGININE METHYL TRANSFERASES | BRISTOL-MYERS SQUIBB COMPANY (US) | 2006-10-26 | — | — | WO | disclosed |