Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 4/20 | 0.44 |
| ▸ | HTR2B | P41595 | 4/20 | 0.37 |
| ▸ | HTR2A | P28223 | 2/20 | 0.37 |
| ▸ | HTR2C | P28335 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CDK4 | P11802 | 2/20 | 0.34 |
| ▸ | CCND1 | P24385 | 2/20 | 0.34 |
| ▸ | HTR1A | P08908 | 2/20 | 0.34 |
| ▸ | HTR7 | P34969 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5823265 | 0.95 | KCNH2 (0.44) | KCNH2HTR2BALDH1A1USP2CYP1A2 | |
| SCHEMBL5818619 | 0.92 | KCNH2 (0.39) | KCNH2HTR2AHTR2CALDH1A1HTR1A | |
| SCHEMBL5818644 | 0.92 | KCNH2 (0.39) | KCNH2HTR2AHTR2CALDH1A1HTR1A | |
| SCHEMBL5818533 | 0.89 | KCNH2 (0.40) | KCNH2HTR2AHTR2CALDH1A1HTR1A | |
| SCHEMBL5820465 | 0.89 | ALDH1A2 (0.39) | KCNH2HTR2BHTR2AHTR2CCDK4 | |
| SCHEMBL5818994 | 0.88 | RCE1 (0.36) | KCNH2HTR2AHTR2CALDH1A1CYP1A2 | |
| SCHEMBL5819016 | 0.88 | KMT2A (0.46) | KCNH2ALDH1A1USP2CYP1A2CYP3A4 | |
| SCHEMBL5817700 | 0.87 | KMT2A (0.48) | KCNH2HTR2BHTR2AHTR2CALDH1A1 | |
| SCHEMBL5820614 | 0.84 | ALDH1A2 (0.41) | KCNH2HTR2BHTR2AHTR2CHTR1A | |
| SCHEMBL5819600 | 0.84 | HTR1A (0.36) | KCNH2HTR2BHTR2AHTR2CCDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006137658-A1 | NEW SUBSTITUTED 1,3-THIAZOLE DERIVATIVES OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF HAVING IMMUNOSUPPRESSION AND INFLAMMATION INHIBITORY ACITIVITY, INTERMEDIATE COMPOUNDS OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF, A PROCESS FOR THE PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | DONGBU HITEK CO., LTD. (KR) | 2006-12-28 | — | — | WO | disclosed |