Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 3/20 | 0.52 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.52 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | HTR2B | P41595 | 2/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9734713 | 0.81 | GABRA1 (0.54) | GABRA1GABRG2GABRB3LMNATSHR | |
| SCHEMBL6215211 | 0.79 | GABRA1 (0.52) | GABRA1GABRG2GABRB3LMNATSHR | |
| SCHEMBL6213612 | 0.79 | GABRA1 (0.76) | GABRA1GABRG2GABRB3LMNATSHR | |
| SCHEMBL3865790 | 0.79 | GABRA1 (0.52) | GABRA1GABRG2GABRB3LMNATSHR | |
| SCHEMBL18629974 | 0.78 | GABRA1 (0.50) | GABRA1GABRG2GABRB3LMNATSHR | |
| SCHEMBL26652091 | 0.76 | GABRA1 (0.48) | GABRA1GABRG2GABRB3LMNATSHR | |
| SCHEMBL19289757 | 0.76 | GABRA1 (0.48) | GABRA1GABRG2GABRB3LMNATSHR | |
| SCHEMBL19289751 | 0.76 | GABRA1 (0.48) | GABRA1GABRG2GABRB3LMNATSHR | |
| SCHEMBL9045163 | 0.75 | GABRA1 (0.47) | GABRA1GABRG2GABRB3LMNATSHR | |
| SCHEMBL19289745 | 0.75 | GABRA1 (0.47) | GABRA1GABRG2GABRB3LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1610779-A1 | 3-OXO-1,3-DIHYDRO-INDAZOLE-2-CARBOXYLIC ACID AMIDE DERIVATIVES AS PHOSPHOLIPASE INHIBITORS | ELI LILLY AND COMPANY (US) | 2006-01-04 | — | — | EP | disclosed |
| WO-2004093872-A1 | 3-OXO-1, 3-DIHYDRO-INDAZOLE-2-CARBOXYLIC ACID AMIDE DERIVATIVES AS PHOSPHOLIPASE INHIBITORS | ELI LILLY AND COMPANY (US) | 2004-11-04 | — | — | WO | disclosed |