Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK1 | Q15118 | 10/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 10/20 | 0.40 |
| ▸ | PDK3 | Q15120 | 10/20 | 0.40 |
| ▸ | PDK4 | Q16654 | 10/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.40 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KLK7 | P49862 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4491393 | 0.83 | KMT2A (0.43) | PDK1PDK2PDK3PDK4HSP90AA1 | |
| SCHEMBL4503272 | 0.83 | KMT2A (0.43) | PDK1PDK2PDK3PDK4HSP90AA1 | |
| SCHEMBL4501038 | 0.83 | KMT2A (0.43) | PDK1PDK2PDK3PDK4HSP90AA1 | |
| SCHEMBL4502357 | 0.81 | KMT2A (0.39) | PDK1PDK2PDK3PDK4HSP90AA1 | |
| SCHEMBL4489743 | 0.81 | KMT2A (0.39) | PDK1PDK2PDK3PDK4HSP90AA1 | |
| SCHEMBL4495844 | 0.81 | KMT2A (0.39) | PDK1PDK2PDK3PDK4HSP90AA1 | |
| SCHEMBL4503738 | 0.78 | ALDH1A1 (0.44) | PTPN1KDM4EALDH1A1MEN1NPC1 | |
| SCHEMBL4497604 | 0.76 | ALDH1A1 (0.48) | PTPN1KDM4EALDH1A1MEN1NPC1 | |
| SCHEMBL4498228 | 0.76 | PDK1 (0.53) | PDK1PDK2PDK3PDK4HSP90AA1 | |
| SCHEMBL4503844 | 0.75 | PDK1 (0.48) | PDK1PDK2PDK3PDK4HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006068928-A1 | PYRROLO[1,2-A]QUINOXALIN-5-(4H)-YL)SULFONYLS AND CARBONYLS AND THEIR USE AS ESTROGENIC AGENTS | WYETH (US) | 2006-06-29 | — | — | WO | disclosed |