Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 11/20 | 0.45 |
| ▸ | ITGA2B | P08514 | 11/20 | 0.45 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.36 |
| ▸ | F2 | P00734 | 3/20 | 0.36 |
| ▸ | F10 | P00742 | 2/20 | 0.36 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.36 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.36 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.36 |
| ▸ | F9 | P00740 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2012562 | 0.92 | ITGB3 (0.38) | ITGB3ITGA2BAOC3KDM4E | |
| SCHEMBL2014777 | 0.91 | ITGB3 (0.38) | ITGB3ITGA2BAOC3KDM4E | |
| SCHEMBL2012955 | 0.90 | ITGB3 (0.37) | ITGB3ITGA2BAOC3 | |
| SCHEMBL2009678 | 0.90 | ITGB3 (0.47) | ITGB3ITGA2BAOC3F2F10 | |
| SCHEMBL2014833 | 0.87 | ITGB3 (0.45) | ITGB3ITGA2BAOC3TPSAB1TPSD1 | |
| SCHEMBL2009871 | 0.86 | GABRA1 (0.37) | ITGB3ITGA2BAOC3KDM4E | |
| SCHEMBL2013047 | 0.85 | ITGB3 (0.45) | ITGB3ITGA2BAOC3F2F10 | |
| SCHEMBL2015632 | 0.84 | ITGB3 (0.53) | ITGB3ITGA2BAOC3F10TPSAB1 | |
| SCHEMBL2010434 | 0.83 | ITGB3 (0.37) | ITGB3ITGA2BAOC3KDM4E | |
| SCHEMBL2009674 | 0.82 | ITGB3 (0.51) | ITGB3ITGA2BAOC3F10TPSAB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1677783-A2 | FIBRINOGEN RECEPTOR ANTAGONISTS AND THEIR USE | Nicholas Piramal India Limited (IN) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005035495-A2 | FIBRINOGEN RECEPTOR ANTAGONISTS AND THEIR USE | NICHOLAS PIRAMAL INDIA LIMITED (IN) | 2005-04-21 | — | — | WO | disclosed |