Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.41 |
| ▸ | ACHE | P22303 | 3/20 | 0.41 |
| ▸ | BCHE | P06276 | 2/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.37 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | SLCO2B1 | O94956 | 1/20 | 0.35 |
| ▸ | TTR | P02766 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | SHBG | P04278 | 1/20 | 0.35 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30123589 | 0.84 | PDE4D (0.47) | ALDH1A1PDE4DACHEBCHEPTPN1 | |
| SCHEMBL29716695 | 0.80 | ALDH1A1 (0.51) | ALDH1A1PDE4DPTPN1CYP19A1CYP3A4 | |
| SCHEMBL4456941 | 0.80 | ALDH1A1 (0.51) | ALDH1A1PDE4DPTPN1CYP19A1CYP3A4 | |
| SCHEMBL29895476 | 0.80 | ALDH1A1 (0.51) | ALDH1A1PDE4DPTPN1CYP19A1CYP3A4 | |
| SCHEMBL707507 | 0.76 | ALDH1A1 (0.46) | ALDH1A1PDE4DACHEBCHEPTPN1 | |
| SCHEMBL19469655 | 0.74 | ALDH1A1 (0.51) | ALDH1A1PTPN1PTGS2CYP19A1CYP3A4 | |
| SCHEMBL30472907 | 0.71 | PTPN1 (0.53) | ALDH1A1PTPN1PTGS2CYP19A1CYP3A4 | |
| SCHEMBL30593801 | 0.70 | ALDH1A1 (0.65) | ALDH1A1PTPN1PTGS2CYP19A1CYP3A4 | |
| SCHEMBL38656303 | 0.69 | ALDH1A1 (0.58) | ALDH1A1PTPN1PTGS2TP53CYP19A1 | |
| SCHEMBL3973540 | 0.69 | ALDH1A1 (0.58) | ALDH1A1PTPN1PTGS2TP53CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101208436-B | Enzymatic demethylation of flavonoids | UNIV GENT | 2012-10-03 | — | — | CN | disclosed |
| CN-1893963-B | Production of hop extracts having oestrogenic and antiproliferative bioactivity | BIODYNAMICS | 2010-09-29 | — | — | CN | disclosed |
| CN-101208436-A | Enzymatic demethylation of flavonoids | UNIV GENT (BE) | 2008-06-25 | — | — | CN | disclosed |
| CN-1893963-A | Production of hop extracts having oestrogenic and antiproliferative bioactivity | BIODYNAMICS (BE) | 2007-01-10 | — | — | CN | disclosed |
| CN-1269942-C | Hop extracts, method for the production and use thereof | SCHWABE WILLMAR GMBH & CO (DE) | 2006-08-16 | — | — | CN | disclosed |
| JP-2006131594-A | CARCINOGENISIS PREVENTING AGENT | UNIV NIHON | 2006-05-25 | — | — | JP | disclosed |
| CN-1541262-A | Hop extracts, method for the production and use thereof | ά�����ʩ�߿˲�ʿ���Ϲ�˾ | 2004-10-27 | — | — | CN | disclosed |