SCHEMBL3973540

SCHEMBL3973540

O=C1CC(O)(c2ccc(O)cc2)Oc2cc(O)cc(O)c21

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.58
RIPK1 Q13546 1/20 0.55
PTPN1 P18031 3/20 0.50
CYP19A1 P11511 5/20 0.47
CYP3A4 P08684 4/20 0.47
CYP1A1 P04798 3/20 0.47
CYP1A2 P05177 3/20 0.47
CYP2C19 P33261 3/20 0.47
CYP1B1 Q16678 3/20 0.47
HSD17B10 Q99714 3/20 0.47
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
CYP2C9 P11712 2/20 0.47
CA12 O43570 2/20 0.47
SLCO2B1 O94956 2/20 0.47
CA4 P22748 2/20 0.47
PSMB5 P28074 2/20 0.47
CA7 P43166 2/20 0.47
ALOX12 P18054 1/20 0.47
TTR P02766 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL38656303 1.00 ALDH1A1 (0.58) ALDH1A1RIPK1PTPN1CYP19A1CYP3A4
SCHEMBL6528998 0.90 RIPK1 (0.59) ALDH1A1RIPK1PTPN1CYP19A1CYP3A4
SCHEMBL30240111 0.89 ALDH1A1 (0.59) ALDH1A1RIPK1PTPN1CYP19A1CYP3A4
SCHEMBL15545294 0.88 ALDH1A1 (0.61) ALDH1A1RIPK1PTPN1CYP19A1CYP3A4
SCHEMBL31074902 0.88 RIPK1 (0.49) ALDH1A1RIPK1PTPN1CYP19A1CYP3A4
SCHEMBL30099859 0.88 RIPK1 (0.49) ALDH1A1RIPK1PTPN1CYP19A1CYP3A4
SCHEMBL30062830 0.86 ALDH1A1 (0.49) ALDH1A1RIPK1PTPN1CYP19A1CYP3A4
SCHEMBL30593801 0.82 ALDH1A1 (0.65) ALDH1A1RIPK1PTPN1CYP19A1CYP3A4
SCHEMBL30428065 0.82 ALDH1A1 (0.57) ALDH1A1RIPK1PTPN1CYP19A1CYP3A4
SCHEMBL15543416 0.80 ALDH1A1 (0.59) ALDH1A1RIPK1PTPN1CYP1A1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 84 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122017082-A Method for detecting 2-hydroxy naringenin in plant 江苏农林职业技术学院 2026-05-12 CN claimed
CN-113265433-B Bifunctional glycosyltransferase and application thereof 中国科学院分子植物科学卓越创新中心 2023-12-26 CN claimed
CN-117187207-A Desmodium styracifolium flavonoid carbon glycoside glycosyltransferase and application of encoding gene thereof 中国科学院华南植物园 2023-12-08 CN claimed
US-20230105024-A1 Bifunctional C-Glycoside Glycosyltransferases and Application Thereof CAS CENTER FOR EXCELLENCE IN MOLECULAR PLANT SCIENCES (CN) 2023-04-06 US claimed
US-20230102194-A1 Novel Flavone Hydroxylases, Microorganism for Synthesizing Flavone C-Glycoside Compounds, and Use Thereof CAS CENTER FOR EXCELLENCE IN MOLECULAR PLANT SCIENCES (CN) 2023-03-30 US claimed
CN-115838699-A Stenoloma chusanum C-glycosyltransferase and coding gene and application thereof 山东大学 2023-03-24 CN claimed
US-20230066984-A1 New Carbon Glycoside Glycosyltransferase and Use Thereof CAS CENTER FOR EXCELLENCE IN MOLECULAR PLANT SCIENCES (CN) 2023-03-02 US claimed
EP-4112732-A1 NOVEL FLAVONE HYDROXYLASES, MICROORGANISM FOR SYNTHESIZING FLAVONE C-GLYCOSIDE COMPOUNDS, AND USE THEREOF CAS Center for Excellence in Molecular Plant Sciences (CN) 2023-01-04 EP claimed
EP-4108777-A1 BIFUNCTIONAL C-GLYCOSIDE GLYCOSYLTRANSFERASES AND APPLICATION THEREOF CAS Center for Excellence in Molecular Plant Sciences (CN) 2022-12-28 EP claimed
EP-4095145-A1 NEW CARBON GLYCOSIDE GLYCOSYLTRANSFERASE AND USE THEREOF CAS Center for Excellence in Molecular Plant Sciences (CN) 2022-11-30 EP claimed
CN-113322288-A Novel flavone hydroxylase, microorganism for synthesizing flavone C-glycosides and application thereof 中国科学院分子植物科学卓越创新中心 2021-08-31 CN claimed
CN-111019919-B Method for synthesizing flavonoid C-glycoside by using lotus flavonoid C-glycosyltransferase UGT708N1 中国科学院植物研究所 2021-08-24 CN claimed
CN-111041056-B Method for synthesizing flavonoid C-glycoside by using lotus flavonoid C-glycosyltransferase UGT708N2 中国科学院植物研究所 2021-08-24 CN claimed
CN-113265433-A Bifunctional carbon glycoside glycosyl transferase and application thereof 中国科学院分子植物科学卓越创新中心 2021-08-17 CN claimed
WO-2021147575-A1 NEW CARBON GLYCOSIDE GLYCOSYLTRANSFERASE AND USE THEREOF 中国科学院分子植物科学卓越创新中心 2021-07-29 WO claimed
CN-113136373-A Novel carbon glycoside glycosyltransferase and application thereof 中国科学院分子植物科学卓越创新中心 2021-07-20 CN claimed
US-20210010056-A1 GLYCOSYLATION MODIFICATION OF BIOACTIVE COMPOUNDS AND DRUGS BY PLANT GLYCOSYLTRANSFERASES (UGTS) UNIV NORTH TEXAS (US) 2021-01-14 US claimed
CN-111041056-A Method for synthesizing flavonoid C-glycoside by using lotus flavonoid C-glycosyltransferase UGT708N2 中国科学院植物研究所 2020-04-21 CN claimed
CN-111019919-A Method for synthesizing flavonoid C-glycoside by using lotus flavonoid C-glycosyltransferase UGT708N1 中国科学院植物研究所 2020-04-17 CN claimed
CN-122017082-A Method for detecting 2-hydroxy naringenin in plant 江苏农林职业技术学院 2026-05-12 CN disclosed
EP-4640834-A1 FLAVANONE 2-HYDROXYLASE GENE AND USE OF SAME Suntory Holdings Limited (JP) 2025-10-29 EP disclosed
CN-118562909-B Method for synthesizing schaftoside or isosaftoside 中国科学院华南植物园 2024-12-17 CN disclosed
CN-118879656-A Dendrobium huoshanense carboglycosyltransferase and application thereof 皖西学院 2024-11-01 CN disclosed
CN-118562909-A Method for synthesizing schaftoside or isosaftoside 中国科学院华南植物园 2024-08-30 CN disclosed
CN-118421660-A Odontopathy euscaphis japonica glycosyltransferase for catalyzing synthesis of carbon glycoside and application thereof 福建农林大学 2024-08-02 CN disclosed
CN-118272400-A EfCGT3 gene related to Gorgon fruit flavonoid C-glycoside synthesis and application 扬州大学 2024-07-02 CN disclosed
WO-2024135619-A1 FLAVANONE 2-HYDROXYLASE GENE AND USE OF SAME サントリーホールディングス株式会社 2024-06-27 WO disclosed
CN-117187207-B Desmodium styracifolium flavonoid carbon glycoside glycosyltransferase and application of encoding gene thereof 中国科学院华南植物园 2024-03-15 CN disclosed
CN-115838699-B Pteridium glaucescens C-glycosyltransferase and encoding gene and application thereof 山东大学 2024-01-05 CN disclosed
CN-113322288-B Novel flavone hydroxylase, microorganism for synthesizing flavone C-glycoside compounds and application thereof 中国科学院分子植物科学卓越创新中心 2023-12-26 CN disclosed
CN-113265433-B Bifunctional glycosyltransferase and application thereof 中国科学院分子植物科学卓越创新中心 2023-12-26 CN disclosed
CN-113322288-B Novel flavone hydroxylase, microorganism for synthesizing flavone C-glycoside compounds and application thereof 中国科学院分子植物科学卓越创新中心 2023-12-26 CN disclosed
CN-117187207-A Desmodium styracifolium flavonoid carbon glycoside glycosyltransferase and application of encoding gene thereof 中国科学院华南植物园 2023-12-08 CN disclosed
CN-113136373-B Carbonoside glycosyltransferase and application thereof 中国科学院分子植物科学卓越创新中心 2023-12-08 CN disclosed
CN-116179504-B Desmodium styracifolium carboglycosyltransferase and application of encoding gene thereof 中国科学院华南植物园 2023-08-15 CN disclosed
CN-116179504-A Desmodium styracifolium carboglycosyltransferase and application of encoding gene thereof 中国科学院华南植物园 2023-05-30 CN disclosed
US-20230105024-A1 Bifunctional C-Glycoside Glycosyltransferases and Application Thereof CAS CENTER FOR EXCELLENCE IN MOLECULAR PLANT SCIENCES (CN) 2023-04-06 US disclosed
US-20230102194-A1 Novel Flavone Hydroxylases, Microorganism for Synthesizing Flavone C-Glycoside Compounds, and Use Thereof CAS CENTER FOR EXCELLENCE IN MOLECULAR PLANT SCIENCES (CN) 2023-03-30 US disclosed
US-20230102194-A1 Novel Flavone Hydroxylases, Microorganism for Synthesizing Flavone C-Glycoside Compounds, and Use Thereof CAS CENTER FOR EXCELLENCE IN MOLECULAR PLANT SCIENCES (CN) 2023-03-30 US disclosed
CN-115838699-A Stenoloma chusanum C-glycosyltransferase and coding gene and application thereof 山东大学 2023-03-24 CN disclosed
CN-115838699-A Stenoloma chusanum C-glycosyltransferase and coding gene and application thereof 山东大学 2023-03-24 CN disclosed
US-20230066984-A1 New Carbon Glycoside Glycosyltransferase and Use Thereof CAS CENTER FOR EXCELLENCE IN MOLECULAR PLANT SCIENCES (CN) 2023-03-02 US disclosed
EP-4112732-A1 NOVEL FLAVONE HYDROXYLASES, MICROORGANISM FOR SYNTHESIZING FLAVONE C-GLYCOSIDE COMPOUNDS, AND USE THEREOF CAS Center for Excellence in Molecular Plant Sciences (CN) 2023-01-04 EP disclosed
EP-4112732-A1 NOVEL FLAVONE HYDROXYLASES, MICROORGANISM FOR SYNTHESIZING FLAVONE C-GLYCOSIDE COMPOUNDS, AND USE THEREOF CAS Center for Excellence in Molecular Plant Sciences (CN) 2023-01-04 EP disclosed
EP-4108777-A1 BIFUNCTIONAL C-GLYCOSIDE GLYCOSYLTRANSFERASES AND APPLICATION THEREOF CAS Center for Excellence in Molecular Plant Sciences (CN) 2022-12-28 EP disclosed
EP-4095145-A1 NEW CARBON GLYCOSIDE GLYCOSYLTRANSFERASE AND USE THEREOF CAS Center for Excellence in Molecular Plant Sciences (CN) 2022-11-30 EP disclosed
CN-111808902-B C-glycosyltransferase and application thereof in synthesis of schaftoside and isoschaftoside 北京大学 2022-11-29 CN disclosed
CN-112961870-B Carbon glycosyltransferase DhCGT2 gene in pseudo-ginseng plant and application thereof 云南农业大学 2022-08-16 CN disclosed
CN-112813084-B Carbon glycosyltransferase DhCGT1 gene in pseudo-anethod plants and application thereof 云南农业大学 2022-07-19 CN disclosed
US-11261477-B2 Glycosylation modification of bioactive compounds and drugs by plant glycosyltransferases (UGTs) UNIVERSITY OF NORTH TEXAS (US) 2022-03-01 US disclosed
CN-113322288-A Novel flavone hydroxylase, microorganism for synthesizing flavone C-glycosides and application thereof 中国科学院分子植物科学卓越创新中心 2021-08-31 CN disclosed
CN-113322288-A Novel flavone hydroxylase, microorganism for synthesizing flavone C-glycosides and application thereof 中国科学院分子植物科学卓越创新中心 2021-08-31 CN disclosed
CN-111019919-B Method for synthesizing flavonoid C-glycoside by using lotus flavonoid C-glycosyltransferase UGT708N1 中国科学院植物研究所 2021-08-24 CN disclosed
CN-111041056-B Method for synthesizing flavonoid C-glycoside by using lotus flavonoid C-glycosyltransferase UGT708N2 中国科学院植物研究所 2021-08-24 CN disclosed
CN-113265433-A Bifunctional carbon glycoside glycosyl transferase and application thereof 中国科学院分子植物科学卓越创新中心 2021-08-17 CN disclosed
WO-2021147575-A1 NEW CARBON GLYCOSIDE GLYCOSYLTRANSFERASE AND USE THEREOF 中国科学院分子植物科学卓越创新中心 2021-07-29 WO disclosed
CN-113136373-A Novel carbon glycoside glycosyltransferase and application thereof 中国科学院分子植物科学卓越创新中心 2021-07-20 CN disclosed
CN-112961870-A Carbon glycosyltransferase DhCGT2 gene in pseudo-ginseng plant and application thereof 云南农业大学 2021-06-15 CN disclosed
CN-112813084-A Carbon glycosyltransferase DhCGT1 gene in pseudo-ginseng plant and application thereof 云南农业大学 2021-05-18 CN disclosed
US-20210010056-A1 GLYCOSYLATION MODIFICATION OF BIOACTIVE COMPOUNDS AND DRUGS BY PLANT GLYCOSYLTRANSFERASES (UGTS) UNIV NORTH TEXAS (US) 2021-01-14 US disclosed
CN-111808902-A C-glycosyltransferase and application thereof in synthesis of schaftoside and isoschaftoside 北京大学 2020-10-23 CN disclosed
CN-111041056-A Method for synthesizing flavonoid C-glycoside by using lotus flavonoid C-glycosyltransferase UGT708N2 中国科学院植物研究所 2020-04-21 CN disclosed
CN-106754989-B Flavanone-2-hydroxylase of microcos paniculata, and coding gene and application thereof 广东药科大学 2020-04-21 CN disclosed
CN-106754989-B Flavanone-2-hydroxylase of microcos paniculata, and coding gene and application thereof 广东药科大学 2020-04-21 CN disclosed
CN-111019919-A Method for synthesizing flavonoid C-glycoside by using lotus flavonoid C-glycosyltransferase UGT708N1 中国科学院植物研究所 2020-04-17 CN disclosed
EP-1726653-B1 Genes coding for Flavone Synthases INT FLOWER DEV PTY LTD (AU) 2009-05-06 EP disclosed
US-7507566-B2 Flavone synthases, methods of using flavone synthases, and plants expressing flavone synthases INTERNATIONAL FLOWER DEVELOPMENTS PROPRIETARY LIMITED (AU) 2009-03-24 US disclosed
US-7465569-B2 Flavone synthases, methods of using flavone synthases, and plants expressing flavone synthases INTERNATIONAL FLOWER DEVELOPMENTS PROPRIETARY LIMITED (AU) 2008-12-16 US disclosed
EP-1728867-B1 Genes coding for flavone synthases INT FLOWER DEV PTY LTD (AU) 2008-10-08 EP disclosed
US-7422881-B2 DNAs coding for flavone synthases, methods of using flavone synthase DNAs, and plants, flowers, and vectors containing flavone synthase DNAs INTERNATIONAL FLOWER DEVELOPMENTS PROPRIETARY LIMITED (AU) 2008-09-09 US disclosed
EP-1067189-B1 GENE ENCODING FLAVONE SYNTHASE INTERNAT FLOWERS DEVELOPMENTS (AU) 2007-08-29 EP disclosed
US-20060277622-A1 DNAs coding for flavone synthases, methods of using flavone synthase DNAs, and plants, flowers, and vectors containing flavone synthase DNAs SUNTORY FLOWERS LIMITED 2006-12-07 US disclosed
US-20060277621-A1 DNAs coding for flavone synthases, methods of using flavone synthase DNAs, and plants, flowers, and vectors containing flavone synthase DNAs SUNTORY FLOWERS LIMITED 2006-12-07 US disclosed
EP-1728867-A2 Genes coding for flavone synthases SUNTORY LIMITED (JP) 2006-12-06 EP disclosed
EP-1726653-A2 GENES CODING FOR FLAVONE SYNTHASES SUNTORY LIMITED (JP) 2006-11-29 EP disclosed
US-20060248609-A1 DNAs coding for flavone synthases, methods of using flavone synthase DNAs, and plants, flowers, and vectors containing flavone synthase DNAs SUNTORY FLOWERS LIMITED 2006-11-02 US disclosed
US-7119253-B2 DNAs coding for flavone synthase, methods of using flavone synthase DNAs, and plants, flowers, and vectors containing flavone synthase DNAs SUNTORY FLOWERS LIMITED (JP) 2006-10-10 US disclosed
US-7119252-B2 DNAs coding for flavone synthesis, methods of using flavone synthase DNAS, and plants, flowers, and vectors containing flavone synthase DNAs SUNTORY LIMITED (JP) 2006-10-10 US disclosed
US-20040261146-A1 Genes coding for flavone synthases SUNTORY LIMITED 2004-12-23 US disclosed
US-20040003431-A1 Genes coding for flavone synthases SUNTORY LIMITED 2004-01-01 US disclosed
US-6596927-B1 Protein of given amino acid sequence, which has activity of synthesizing flavones from flavanones; transforming a plant to alter the flower colors SUNTORY LIMITED (JP) 2003-07-22 US disclosed
EP-1114162-A1 GENES CODING FOR FLAVONE SYNTHASES SUNTORY LIMITED (JP) 2001-07-11 EP disclosed
WO-2001005981-A1 GENES CODING FOR FLAVONE SYNTHASES SUNTORY LIMITED (JP) 2001-01-25 WO disclosed
EP-1067189-A1 GENE ENCODING FLAVONE SYNTHASE SUNTORY LIMITED (JP) 2001-01-10 EP disclosed
EP-1067189-A1 GENE ENCODING FLAVONE SYNTHASE SUNTORY LIMITED (JP) 2001-01-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230066984-A1 New Carbon Glycoside Glycosyltransferase and Use Thereof UGGT1, UGDH, UGCG ALDH1A1 1239/4885RIPK1 2614/4885PTPN1 4855/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.