Known targets — ChEMBL curated mechanism
ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3CHRM1CHRM2CHRM3CHRM4ESR1ESR2GABRA1GABRB1GABRG2GBA1HRH1HTR1DHTR2AOPRD1OPRK1OPRM1SLC6A2SLC6A3TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Cadaverine Tartrate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 known ✓ | P07550 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | CASR | P41180 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | LDHA | P00338 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cadaverine Tartrate SCHEMBL5825857 | 1.00 | KMT2A (0.59) | KMT2AMEN1CASRLMNAMAPK1 | |
| SCHEMBL4073722 | 0.90 | CASR (0.62) | KMT2AMEN1CASRLMNAALDH1A1 | |
| SCHEMBL29551865 | 0.90 | CASR (0.62) | KMT2AMEN1CASRLMNAALDH1A1 | |
| SCHEMBL607183 | 0.90 | CASR (0.62) | KMT2AMEN1CASRLMNAALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL29551765 | 0.87 | CASR (0.61) | KMT2AMEN1CASRLMNAMAPK1 | |
| Trifluoroacetic Acid SCHEMBL28937395 | 0.87 | CASR (0.61) | KMT2AMEN1CASRLMNAMAPK1 | |
| SCHEMBL14469768 | 0.82 | CASR (0.58) | KMT2AMEN1CASRLMNAMAPK1 | |
| SCHEMBL13868189 | 0.79 | CASR (0.73) | KMT2AMEN1CASRLMNAALDH1A1 | |
| Hydrochloric Acid SCHEMBL30527154 | 0.79 | LMNA (0.64) | KMT2AMEN1LMNAMAPK1ALDH1A1 | |
| SCHEMBL4886486 | 0.78 | KMT2A (0.60) | KMT2AMEN1LMNAMAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2006225272-A | (R)-N-(3,4-DIMETHOXYBENZYL)-1-PHENYLETHYLAMINE L-TARTRATE AND METHOD OF PURIFYING (R)-N-(3,4-DIMETHOXYBENZYL)-1-PHENYLETHYLAMINE USING THE SAME | SUMITOMO CHEMICAL CO LTD | 2006-08-31 | — | — | JP | disclosed |
| CN-1821190-A | Purifying method of (r)-n-(3,4-dimethoxy benzyl)-1-phenylethylamine l-tartrate and purifying method of (r)-n-(3,4-dimethoxy benzyl)-1-phenylethylamine | SUMITOMO CHEMICAL CO (JP) | 2006-08-23 | — | — | CN | disclosed |