Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | DDR1 | Q08345 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.39 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.39 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL582743 | 1.00 | CETP (0.44) | CETPKMT2ALMNANPSR1L3MBTL1 | |
| SCHEMBL582690 | 0.94 | KMT2A (0.44) | CETPKMT2ALMNANPSR1L3MBTL1 | |
| SCHEMBL5521185 | 0.94 | KMT2A (0.44) | CETPKMT2ALMNANPSR1L3MBTL1 | |
| SCHEMBL582894 | 0.94 | KMT2A (0.44) | CETPKMT2ALMNANPSR1L3MBTL1 | |
| SCHEMBL5513992 | 0.92 | KMT2A (0.46) | CETPKMT2ALMNANPSR1L3MBTL1 | |
| SCHEMBL5517353 | 0.92 | KMT2A (0.46) | CETPKMT2ALMNANPSR1L3MBTL1 | |
| SCHEMBL582826 | 0.92 | KMT2A (0.46) | CETPKMT2ALMNANPSR1L3MBTL1 | |
| SCHEMBL582742 | 0.91 | POLB (0.44) | CETPKMT2ALMNANPSR1L3MBTL1 | |
| SCHEMBL582729 | 0.81 | P2RX7 (0.43) | CETPKMT2ALMNADDR1SUCNR1 | |
| SCHEMBL5517336 | 0.81 | P2RX7 (0.43) | CETPKMT2ALMNADDR1SUCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1755572-B1 | N- (2-BENZYL) -2-PHENYLBUTANAMIDES AS ANDROGEN RECEPTOR MODULATORS | MERCK SHARP & DOHME (US) | 2012-02-15 | — | — | EP | disclosed |