Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 8/20 | 0.84 |
| ▸ | TOP1 | P11387 | 16/20 | 0.60 |
| ▸ | PRKD3 | O94806 | 4/20 | 0.52 |
| ▸ | PRKCG | P05129 | 4/20 | 0.52 |
| ▸ | PRKCB | P05771 | 4/20 | 0.52 |
| ▸ | PRKCH | P24723 | 4/20 | 0.52 |
| ▸ | PRKCI | P41743 | 4/20 | 0.52 |
| ▸ | PRKCE | Q02156 | 4/20 | 0.52 |
| ▸ | PRKCQ | Q04759 | 4/20 | 0.52 |
| ▸ | PRKCZ | Q05513 | 4/20 | 0.52 |
| ▸ | PRKCD | Q05655 | 4/20 | 0.52 |
| ▸ | PRKD1 | Q15139 | 4/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5827594 | 0.86 | PRKCA (0.77) | PRKCATOP1 | |
| SCHEMBL5827663 | 0.85 | PRKCA (0.79) | PRKCATOP1 | |
| SCHEMBL6730339 | 0.83 | PRKCA (0.88) | PRKCATOP1PRKCQ | |
| SCHEMBL5982059 | 0.81 | PRKCA (0.80) | PRKCATOP1 | |
| SCHEMBL8500729 | 0.79 | TOP1 (0.81) | PRKCATOP1PRKD3PRKCGPRKCB | |
| SCHEMBL5827931 | 0.79 | PRKCA (0.64) | PRKCATOP1 | |
| SCHEMBL5828684 | 0.79 | PRKCA (0.66) | PRKCATOP1 | |
| SCHEMBL5828476 | 0.79 | PRKCA (0.54) | PRKCATOP1PRKCQ | |
| SCHEMBL5786888 | 0.79 | PRKCA (0.70) | PRKCATOP1PRKD3PRKCGPRKCB | |
| SCHEMBL5827704 | 0.78 | PRKCA (0.65) | PRKCATOP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7001906-B2 | Pyrido-pyrido-pyrrolo pyrrolo-indole and pyrido-pyrrolo pyrrolo carbazole derivatives, method for the production thereof and pharmaceutical compositions containing said derivatives | LES LABORATOIRES SERVIER (FR) | 2006-02-21 | — | — | US | disclosed |
| US-20040152721-A1 | Pyrido-pyrido-pyrrolo pyrrolo-indole and pyrido-pyrrolo pyrrolo carbazole derivatives, method for the production thereof and pharmaceutical compositions containing said derivatives | LES LABORATOIRES SERVIER (FR) | 2004-08-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040152721-A1 | Pyrido-pyrido-pyrrolo pyrrolo-indole and pyrido-pyrrolo pyrrolo carbazole derivatives, method for the production thereof and pharmaceutical compositions containing said derivatives | PYM1, PNPO, IDO1 | PRKCA 3464/4885TOP1 243/4885PRKD3 227/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.