Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 1/20 | 0.33 |
| ▸ | NCF1 | P14598 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL6190136 | 0.91 | BRD4 (0.30) | BRD4 | |
| SCHEMBL25802167 | 0.81 | NCF1 (0.32) | NCF1 | |
| SCHEMBL12604722 | 0.81 | NCF1 (0.32) | NCF1 | |
| SCHEMBL5828687 | 0.79 | NCF1 (0.31) | NCF1 | |
| SCHEMBL24069633 | 0.78 | BRD4 (0.36) | APLNRBRD4 | |
| SCHEMBL24070905 | 0.78 | BRD4 (0.36) | APLNRBRD4 | |
| SCHEMBL20794956 | 0.77 | — | — | |
| SCHEMBL18896104 | 0.73 | — | — | |
| SCHEMBL9813720 | 0.73 | APLNR (0.44) | APLNRBRD4 | |
| SCHEMBL17382102 | 0.71 | GAA (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1441718-A4 | CARBINOLS FOR THE TREATMENT OF NEUROPATHIC DYSFUNCTION | ENDO PHARMACEUTICALS INC (US) | 2005-08-17 | — | — | EP | claimed |
| CN-1599607-A | Methanol for treating nerve dysfunction | ENDO PHARMACEUTICALS INC (US) | 2005-03-23 | — | — | CN | claimed |
| EP-1441718-A2 | CARBINOLS FOR THE TREATMENT OF NEUROPATHIC DYSFUNCTION | Endo Pharmaceuticals Inc. (US) | 2004-08-04 | — | — | EP | claimed |
| WO-2003032910-A2 | CARBINOLS FOR THE TREATMENT OF NEUROPATHIC DYSFUNCTION | ENDO PHARMACEUTICALS INC. (US) | 2003-04-24 | — | — | WO | claimed |
| US-7001904-B1 | Guanidine derivatives quinazoline and quinoline for use in the treatment of autoimmune diseases | ASTRAZENECA AB (SE) | 2006-02-21 | — | — | US | disclosed |
| EP-1441718-A4 | CARBINOLS FOR THE TREATMENT OF NEUROPATHIC DYSFUNCTION | ENDO PHARMACEUTICALS INC (US) | 2005-08-17 | — | — | EP | disclosed |
| CN-1599607-A | Methanol for treating nerve dysfunction | ENDO PHARMACEUTICALS INC (US) | 2005-03-23 | — | — | CN | disclosed |
| EP-1441718-A2 | CARBINOLS FOR THE TREATMENT OF NEUROPATHIC DYSFUNCTION | Endo Pharmaceuticals Inc. (US) | 2004-08-04 | — | — | EP | disclosed |
| WO-2003032910-A2 | CARBINOLS FOR THE TREATMENT OF NEUROPATHIC DYSFUNCTION | ENDO PHARMACEUTICALS INC. (US) | 2003-04-24 | — | — | WO | disclosed |