Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5170081 | 0.85 | GAA (0.42) | HSD17B10ALDH1A1MAPTKMT2AL3MBTL1 | |
| SCHEMBL8554773 | 0.81 | ALDH1A1 (0.54) | HSD17B10ALDH1A1PKMNPSR1LMNA | |
| SCHEMBL5828966 | 0.78 | HSD17B10 (0.48) | HSD17B10ALDH1A1PKMNPSR1LMNA | |
| SCHEMBL8695133 | 0.77 | KMT2A (0.57) | HSD17B10ALDH1A1PKMNPSR1LMNA | |
| SCHEMBL5828523 | 0.76 | ACE (0.42) | ALDH1A1L3MBTL1POLBCYP2C9ACE | |
| SCHEMBL5166125 | 0.73 | PPARG (0.41) | ALDH1A1KMT2AL3MBTL1POLBCYP2C9 | |
| SCHEMBL8552221 | 0.72 | MDM2 (0.44) | HSD17B10ALDH1A1PKMMAPTKMT2A | |
| SCHEMBL5167607 | 0.71 | GAA (0.44) | ALDH1A1L3MBTL1POLBCYP2C9CYP2C19 | |
| SCHEMBL8551199 | 0.71 | ALDH1A1 (0.43) | HSD17B10ALDH1A1PKMNPSR1MAPT | |
| SCHEMBL8552104 | 0.71 | ALDH1A1 (0.42) | HSD17B10ALDH1A1PKMNPSR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7084244-B2 | Conformationally constrained backbone cyclized peptide analogs | DEVELOGEN ISRAEL LTD. (IL) | 2006-08-01 | — | — | US | disclosed |
| US-20030144186-A1 | Conformationally constrained backbone cyclized peptide analogs | DEVELOGEN ISRAEL LTD. (IL) | 2003-07-31 | — | — | US | disclosed |
| US-6407059-B1 | SOMATOSTATIN-TYPE DRUG | PEPTOR LIMITED (IL) | 2002-06-18 | — | — | US | disclosed |
| US-6265375-B1 | Conformationally constrained backbone cyclized peptide analogs | YISSUM RESEARCH DEVELOPMENT CO. OF THE HEBREW UNIVERSITY (IL) | 2001-07-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030144186-A1 | Conformationally constrained backbone cyclized peptide analogs | VIP, BDKRB1, BDKRB2 | HSD17B10 4629/4885ALDH1A1 4862/4885PKM 1199/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.