Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 7/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | MMP12 | P39900 | 1/20 | 0.42 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 6/20 | 0.39 |
| ▸ | CA1 | P00915 | 6/20 | 0.39 |
| ▸ | CA9 | Q16790 | 6/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.38 |
| ▸ | FYN | P06241 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7147524 | 1.00 | CYP2D6 (0.49) | CYP2D6THRBHSD17B10BCHECA2 | |
| SCHEMBL4499808 | 1.00 | CYP2D6 (0.49) | CYP2D6THRBHSD17B10BCHECA2 | |
| SCHEMBL4499805 | 1.00 | CYP2D6 (0.49) | CYP2D6THRBHSD17B10BCHECA2 | |
| SCHEMBL7154746 | 1.00 | CYP2D6 (0.49) | CYP2D6THRBHSD17B10BCHECA2 | |
| SCHEMBL7154743 | 1.00 | CYP2D6 (0.49) | CYP2D6THRBHSD17B10BCHECA2 | |
| SCHEMBL8744183 | 0.89 | CYP2D6 (0.51) | CYP2D6THRBHSD17B10BCHECA2 | |
| SCHEMBL7155622 | 0.89 | CYP2D6 (0.51) | CYP2D6THRBHSD17B10BCHECA2 | |
| SCHEMBL7045459 | 0.89 | CYP2D6 (0.51) | CYP2D6THRBHSD17B10BCHECA2 | |
| SCHEMBL7155618 | 0.89 | CYP2D6 (0.51) | CYP2D6THRBHSD17B10BCHECA2 | |
| SCHEMBL570264 | 0.89 | CYP2D6 (0.51) | CYP2D6THRBHSD17B10BCHECA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7018824-B2 | Mannosyl transfer with regeneration of GDP-mannose | THE SCRIPPS RESEARCH INSTITUTE (US) | 2006-03-28 | — | — | US | disclosed |
| US-20050221447-A1 | water soluble transferase enzyme polypeptides, coded by exogenous DNA; glycosylation | THE SCRIPPS RESEARCH INSTITUTE | 2005-10-06 | — | — | US | disclosed |
| US-6919440-B2 | Mannosyl transfer with regeneration of GDP-mannose | THE SCRIPPS RESEARCH INSTITUTE (US) | 2005-07-19 | — | — | US | disclosed |
| US-20030119090-A1 | Mannosyl transfer with regeneration of GDP-mannose | WONG CHI-HUEY (US) | 2003-06-26 | — | — | US | disclosed |
| US-6485930-B1 | Mannosyl transfer with regeneration of GDP-mannose | THE SCRIPPS RESEARCH INSTITUTE | 2002-11-26 | — | — | US | disclosed |