Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 7/20 | 0.50 |
| ▸ | OGA | O60502 | 1/20 | 0.45 |
| ▸ | P4HB | P07237 | 1/20 | 0.41 |
| ▸ | PDIA4 | P13667 | 1/20 | 0.41 |
| ▸ | PDIA3 | P30101 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.40 |
| ▸ | FYN | P06241 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 6/20 | 0.39 |
| ▸ | CA1 | P00915 | 5/20 | 0.39 |
| ▸ | CA9 | Q16790 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7155618 | 1.00 | CYP2D6 (0.51) | CYP2D6THRBHSD17B10CA2OGA | |
| SCHEMBL570264 | 1.00 | CYP2D6 (0.51) | CYP2D6THRBHSD17B10CA2OGA | |
| SCHEMBL8744183 | 1.00 | CYP2D6 (0.51) | CYP2D6THRBHSD17B10CA2OGA | |
| SCHEMBL7045455 | 1.00 | CYP2D6 (0.51) | CYP2D6THRBHSD17B10CA2OGA | |
| SCHEMBL7155622 | 1.00 | CYP2D6 (0.51) | CYP2D6THRBHSD17B10CA2OGA | |
| SCHEMBL7154743 | 0.89 | CYP2D6 (0.49) | CYP2D6THRBHSD17B10CA2OGA | |
| SCHEMBL7154746 | 0.89 | CYP2D6 (0.49) | CYP2D6THRBHSD17B10CA2OGA | |
| SCHEMBL7147524 | 0.89 | CYP2D6 (0.49) | CYP2D6THRBHSD17B10CA2OGA | |
| SCHEMBL4499808 | 0.89 | CYP2D6 (0.49) | CYP2D6THRBHSD17B10CA2OGA | |
| SCHEMBL5829404 | 0.89 | CYP2D6 (0.49) | CYP2D6THRBHSD17B10CA2OGA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030119762-A1 | 5'-substituted-ribofuranosyl benzimidazoles as antiviral agents | TOWNSEND LEROY B (US) | 2003-06-26 | — | — | US | disclosed |
| EP-0845001-B1 | 5'-SUBSTITUTED-RIBOFURANOSYL BENZIMIDAZOLES AS ANTIVIRAL AGENTS | UNIV MICHIGAN (US) | 2002-11-13 | — | — | EP | disclosed |
| US-20010011075-A1 | 5'-SUBSTITUTED-RIBOFURANOSYL BENZIMIDAZOLES AS ANTIVIRAL AGENTS | TOWNSEND LEROY B (US) | 2001-08-02 | — | — | US | disclosed |
| US-5874413-A | CYTOMEGALO VIRUS | UNIVERSITY OF MICHIGAN (US) | 1999-02-23 | — | — | US | disclosed |
| EP-0845001-A1 | 5'-SUBSTITUTED-RIBOFURANOSYL BENZIMIDAZOLES AS ANTIVIRAL AGENTS | The Regents of The University of Michigan (US) | 1998-06-03 | — | — | EP | disclosed |
| WO-1997007125-A1 | 5'-SUBSTITUTED-RIBOFURANOSYL BENZIMIDAZOLES AS ANTIVIRAL AGENTS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 1997-02-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030119762-A1 | 5'-substituted-ribofuranosyl benzimidazoles as antiviral agents | ZC3HAV1, ZC3HAV1L, IFNAR1 | CYP2D6 515/4885THRB 3675/4885HSD17B10 3111/4885 |
| US-20010011075-A1 | 5'-SUBSTITUTED-RIBOFURANOSYL BENZIMIDAZOLES AS ANTIVIRAL AGENTS | ZC3HAV1, ZC3HAV1L, IFNAR1 | CYP2D6 515/4885THRB 3675/4885HSD17B10 3111/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.