SCHEMBL8744183

SCHEMBL8744183

CC(=O)OC1OC(CBr)C(OC(C)=O)C(OC(C)=O)C1OC(C)=O

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 2/20 0.51
THRB P10828 1/20 0.51
HSD17B10 Q99714 1/20 0.51
CA2 P00918 7/20 0.50
OGA O60502 1/20 0.45
P4HB P07237 1/20 0.41
PDIA4 P13667 1/20 0.41
PDIA3 P30101 1/20 0.41
TSHR P16473 1/20 0.40
NR3C1 P04150 1/20 0.40
FYN P06241 1/20 0.40
ADRA2A P08913 1/20 0.40
ADORA3 P0DMS8 1/20 0.40
ADRA2B P18089 1/20 0.40
DRD4 P21917 1/20 0.40
DRD3 P35462 1/20 0.40
CA12 O43570 6/20 0.39
CA1 P00915 5/20 0.39
CA9 Q16790 4/20 0.39
MAPT P10636 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7155618 1.00 CYP2D6 (0.51) CYP2D6THRBHSD17B10CA2OGA
SCHEMBL7045459 1.00 CYP2D6 (0.51) CYP2D6THRBHSD17B10CA2OGA
SCHEMBL570264 1.00 CYP2D6 (0.51) CYP2D6THRBHSD17B10CA2OGA
SCHEMBL7045455 1.00 CYP2D6 (0.51) CYP2D6THRBHSD17B10CA2OGA
SCHEMBL7155622 1.00 CYP2D6 (0.51) CYP2D6THRBHSD17B10CA2OGA
SCHEMBL7154743 0.89 CYP2D6 (0.49) CYP2D6THRBHSD17B10CA2OGA
SCHEMBL7154746 0.89 CYP2D6 (0.49) CYP2D6THRBHSD17B10CA2OGA
SCHEMBL7147524 0.89 CYP2D6 (0.49) CYP2D6THRBHSD17B10CA2OGA
SCHEMBL4499808 0.89 CYP2D6 (0.49) CYP2D6THRBHSD17B10CA2OGA
SCHEMBL5829404 0.89 CYP2D6 (0.49) CYP2D6THRBHSD17B10CA2OGA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103561716-B Hair growing and restoring agent INSTITUTE OF RHEOLOGICAL FUNCTION OF FOOD CO.,LTD. (JP) 2016-04-27 CN disclosed
CN-102791753-B Polymers comprising a majority of amphiphilic monomers intended for trapping and manipulating membrane proteins CENTRE NAT RECH SCIENT 2015-06-17 CN disclosed
CN-103561716-A Hair growing and restoring agent INST OF RHEOLOGICAL FUNCTION OF FOOD CO LTD 2014-02-05 CN disclosed
CN-102791753-A Polymers comprising a majority of amphiphilic monomers intended for trapping and manipulating membrane proteins CENTRE NAT RECH SCIENT 2012-11-21 CN disclosed
CN-101340893-B Intranasal administration of rapid acting insulin NASTECH PHARM CO 2012-03-21 CN disclosed
CN-101340893-A Intranasal administration of rapid acting insulin NASTECH PHARM CO (US) 2009-01-07 CN disclosed
CN-1671724-A Prodrug, medicinal utilization thereof and process for producing the same NIPPON SUISAN KAISHA LTD (JP) 2005-09-21 CN disclosed
EP-0751947-A1 GLUCOSIDIC DERIVATIVES OF N-ACYL ALKYLAMINES EXERTING NEUROPROTECTIVE, NEUROTROPHIC AND ANTI-INFLAMMATORY ACTION, USEFUL IN ACUTE AND CHRONIC DISORDERS OF THE CENTRAL NERVOUS SYSTEM CONNECTED WITH EXCITOTOXICITY LIFEGROUP S.p.A. (IT) 1997-01-08 EP disclosed
WO-1995025736-A1 GLUCOSIDIC DERIVATIVES OF N-ACYL ALKYLAMINES EXERTING NEUROPROTECTIVE, NEUROTROPHIC AND ANTI-INFLAMMATORY ACTION, USEFUL IN ACUTE AND CHRONIC DISORDERS OF THE CENTRAL NERVOUS SYSTEM CONNECTED WITH EXCITOTOXICITY LIFEGROUP S.P.A. (IT) 1995-09-28 WO disclosed
WO-1994002586-A2 REPRESSION OF VIRULENT GENE EXPRESSION AGRICULTURAL AND FOOD RESEARCH COUNCIL (GB) 1994-02-03 WO disclosed
US-4260603-A Sterol glycoside with activity as prostaglandin synthetase inhibitor HOYER GMBH & CO. KG (DE) 1981-04-07 US disclosed
US-4188379-A Sterolins and their use ROECAR HOLDINGS (NETHERLANDS ANTILLES) N.V. (AN) 1980-02-12 US disclosed