Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 16/20 | 1.00 |
| ▸ | ADORA2A | P29274 | 10/20 | 0.70 |
| ▸ | ADORA1 | P30542 | 7/20 | 0.70 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3060342 | 0.84 | ADORA3 (0.73) | ADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL3060344 | 0.84 | ADORA3 (0.73) | ADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL4345670 | 0.84 | ADORA3 (0.72) | ADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL5829488 | 0.82 | ADORA3 (0.70) | ADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL19583012 | 0.80 | ADORA3 (0.72) | ADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL17824401 | 0.80 | ADORA3 (1.00) | ADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL3068488 | 0.80 | ADORA3 (1.00) | ADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL639767 | 0.80 | ADORA3 (1.00) | ADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL639768 | 0.80 | ADORA3 (1.00) | ADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL29386433 | 0.80 | ADORA3 (1.00) | ADORA3ADORA2AADORA1ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7087589-B2 | Methanocarba cycloakyl nucleoside analogues | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2006-08-08 | — | — | US | disclosed |