Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 14/20 | 0.73 |
| ▸ | ADORA2A | P29274 | 8/20 | 0.71 |
| ▸ | ADORA1 | P30542 | 7/20 | 0.71 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.70 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.70 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.70 |
| ▸ | MAPT | P10636 | 1/20 | 0.70 |
| ▸ | LMNA | P02545 | 1/20 | 0.70 |
| ▸ | BLM | P54132 | 1/20 | 0.70 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.70 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.70 |
| ▸ | PKM | P14618 | 1/20 | 0.70 |
| ▸ | TSHR | P16473 | 1/20 | 0.70 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.70 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.70 |
| ▸ | HTR2C | P28335 | 1/20 | 0.70 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.70 |
| ▸ | HTR2B | P41595 | 1/20 | 0.70 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.70 |
| ▸ | PPARD | Q03181 | 1/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3060344 | 1.00 | ADORA3 (0.73) | ADORA3ADORA2AADORA1CYP3A4MAPK1 | |
| SCHEMBL4345670 | 0.86 | ADORA3 (0.72) | ADORA3ADORA2AADORA1CYP3A4MAPK1 | |
| SCHEMBL5829486 | 0.84 | ADORA3 (1.00) | ADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL12501676 | 0.83 | ADORA3 (0.74) | ADORA3ADORA2AADORA1CYP3A4MAPK1 | |
| SCHEMBL19503866 | 0.83 | ADORA3 (0.75) | ADORA3ADORA2AADORA1CYP3A4MAPK1 | |
| SCHEMBL18675571 | 0.82 | ADORA3 (1.00) | ADORA3ADORA2AADORA1PPARD | |
| Ib-Meca SCHEMBL20905217 | 0.82 | ADORA3 (1.00) | ADORA3ADORA2AADORA1CYP3A4MAPK1 | |
| Ib-Meca SCHEMBL10089244 | 0.82 | ADORA3 (1.00) | ADORA3ADORA2AADORA1CYP3A4MAPK1 | |
| Ib-Meca SCHEMBL8922766 | 0.82 | ADORA3 (1.00) | ADORA3ADORA2AADORA1CYP3A4MAPK1 | |
| Ib-Meca SCHEMBL448115 | 0.82 | ADORA3 (1.00) | ADORA3ADORA2AADORA1CYP3A4MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7790735-B2 | Methanocarba cycloalkyl nucleoside analogues | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2010-09-07 | — | — | US | disclosed |
| US-20100222369-A1 | TREATMENT FOR DRY EYE CONDITIONS | CAN-FITE BIOPHARMA LTD. (IL) | 2010-09-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100222369-A1 | TREATMENT FOR DRY EYE CONDITIONS | ADORA3, ADORA2A, ADORA2B | ADORA3 1/4885ADORA2A 2/4885ADORA1 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.