Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | PLA2G4B | P0C869 | 5/20 | 0.51 |
| ▸ | DGKA | P23743 | 1/20 | 0.50 |
| ▸ | RARB | P10826 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cetyl Palmitate SCHEMBL8430810 | 0.92 | TSHR (0.60) | TSHRTP53PLA2G4BDGKARARB | |
| Azelaic Acid SCHEMBL5701685 | 0.88 | TSHR (0.56) | TSHRTP53PLA2G4BDGKARARB | |
| Octanoic Acid SCHEMBL17797787 | 0.87 | CES2 (0.51) | TSHRTP53PLA2G4BALDH1A1 | |
| Dodecanoate SCHEMBL6139344 | 0.87 | CES2 (0.51) | TSHRTP53PLA2G4BALDH1A1 | |
| Decanoic Acid SCHEMBL17797876 | 0.87 | CES2 (0.51) | TSHRTP53PLA2G4BALDH1A1 | |
| Triethylene Glycol SCHEMBL12971248 | 0.86 | MEN1 (0.61) | TSHRTP53PLA2G4BRARBHTT | |
| Benzoic Acid SCHEMBL11325743 | 0.86 | TSHR (0.55) | TSHRTP53PLA2G4BRARBHTT | |
| Tetraethylene Glycol SCHEMBL17797838 | 0.85 | CES2 (0.50) | TSHRTP53PLA2G4BHTTALDH1A1 | |
| Dodecanoate SCHEMBL17797828 | 0.85 | CES2 (0.50) | TSHRTP53PLA2G4BHTTALDH1A1 | |
| Decanoic Acid SCHEMBL17797874 | 0.85 | CES2 (0.50) | TSHRTP53PLA2G4BHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7081503-B2 | Process producing vinyl polymer having alkenyl group at end, vinyl polymer, and curable composition | KANEKA CORPORATION (JP) | 2006-07-25 | — | — | US | disclosed |
| US-7009004-B2 | Process for producing vinyl polymer having alkenyl group at end vinyl polymer and curable composition | KANEKA CORPORATION (JP) | 2006-03-07 | — | — | US | disclosed |
| US-20060004171-A1 | Process for producing vinyl polymer having alkenyl group at end, vinyl polymer, and curable composition | TSUJI RYOTARO | 2006-01-05 | — | — | US | disclosed |
| US-20040097678-A1 | Process for producing vinyl polymer having alkenyl group at end vinyl polymer and curable composition | KANEKA CORPORATION (JP) | 2004-05-20 | — | — | US | disclosed |
| EP-1375531-A1 | PROCESS FOR PRODUCING VINYL POLYMER HAVING ALKENYL GROUP AT END, VINYL POLYMER, AND CURABLE COMPOSITION | KANEKA CORPORATION (JP) | 2004-01-02 | — | — | EP | disclosed |