SCHEMBL5831001

SCHEMBL5831001

C=CCc1ccccc1C(=S)OC

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.42
ALDH1A1 P00352 1/20 0.41
KDM4E B2RXH2 3/20 0.41
MEN1 O00255 1/20 0.41
HTT P42858 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
GABRA1 P14867 1/20 0.41
GABRB2 P47870 1/20 0.41
ADRB2 P07550 3/20 0.40
ADRB1 P08588 3/20 0.40
LMNA P02545 2/20 0.40
HTR1A P08908 1/20 0.40
ADRB3 P13945 1/20 0.40
ADRA2C P18825 1/20 0.40
SLC6A2 P23975 1/20 0.40
BDKRB2 P30411 1/20 0.40
SLC6A4 P31645 1/20 0.40
ADRA1A P35348 1/20 0.40
HTR2B P41595 1/20 0.40
KCNH2 Q12809 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7591364 0.80 GABRA1 (0.44) KMT2AALDH1A1KDM4EMEN1HTT
SCHEMBL24074659 0.79 ALDH1A1 (0.57) KMT2AALDH1A1KDM4EMEN1HTT
Benzene SCHEMBL27474312 0.78 GABRA1 (0.46) KMT2AALDH1A1KDM4EMEN1HTT
SCHEMBL10951024 0.78 ALDH1A1 (0.43) KMT2AALDH1A1HTTGABRA1GABRB2
SCHEMBL5834460 0.78 GABRA1 (0.46) KMT2AALDH1A1KDM4EMEN1HTT
SCHEMBL11663743 0.77 KDM4E (0.44) KMT2AALDH1A1KDM4EMEN1HTT
SCHEMBL11231560 0.77 GABRA1 (0.44) KMT2AALDH1A1KDM4EGABRA1GABRB2
SCHEMBL27648081 0.77 GABRA1 (0.44) KMT2AALDH1A1KDM4EMEN1HTT
SCHEMBL18889553 0.77 ALDH1A1 (0.41) KMT2AALDH1A1KDM4EHTTLMNA
SCHEMBL1262603 0.77 GABRA1 (0.44) KMT2AALDH1A1KDM4EMEN1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7081503-B2 Process producing vinyl polymer having alkenyl group at end, vinyl polymer, and curable composition KANEKA CORPORATION (JP) 2006-07-25 US disclosed
US-7009004-B2 Process for producing vinyl polymer having alkenyl group at end vinyl polymer and curable composition KANEKA CORPORATION (JP) 2006-03-07 US disclosed
US-20060004171-A1 Process for producing vinyl polymer having alkenyl group at end, vinyl polymer, and curable composition TSUJI RYOTARO 2006-01-05 US disclosed
US-20050004318-A1 Curable composition OHSHIRO NOBUAKI (JP) 2005-01-06 US disclosed
EP-1452550-A1 CURABLE COMPOSITION KANEKA CORPORATION (JP) 2004-09-01 EP disclosed
US-20040097678-A1 Process for producing vinyl polymer having alkenyl group at end vinyl polymer and curable composition KANEKA CORPORATION (JP) 2004-05-20 US disclosed
EP-1375531-A1 PROCESS FOR PRODUCING VINYL POLYMER HAVING ALKENYL GROUP AT END, VINYL POLYMER, AND CURABLE COMPOSITION KANEKA CORPORATION (JP) 2004-01-02 EP disclosed