SCHEMBL5831071

SCHEMBL5831071

CC(C)N(C(C)C)P(OCc1ccccc1)OC(Cl)(Cl)CCl

nearest known ligand 0.32

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.32
KMT2A Q03164 1/20 0.31
TRPA1 O75762 1/20 0.30
ALDH1A1 P00352 2/20 0.30
SLC22A2 O15244 1/20 0.30
SLC22A1 O15245 1/20 0.30
SLC22A3 O75751 1/20 0.30
ESR1 P03372 1/20 0.30
CHRM2 P08172 1/20 0.30
HTR1A P08908 1/20 0.30
ADRA2A P08913 1/20 0.30
ADORA3 P0DMS8 1/20 0.30
CHRM1 P11229 1/20 0.30
DRD2 P14416 1/20 0.30
ADRA2B P18089 1/20 0.30
ADRA2C P18825 1/20 0.30
CHRM3 P20309 1/20 0.30
DRD1 P21728 1/20 0.30
SLC6A2 P23975 1/20 0.30
HTR2A P28223 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL80897 0.83 TSHR (0.41) TSHRKMT2AALDH1A1ADRA2BADRA2C
SCHEMBL5831072 0.81 CA1 (0.33) TSHRKMT2AALDH1A1LMNAHPGD
Acetonitrile SCHEMBL27856444 0.76 MAOB (0.37) TSHRKMT2AALDH1A1IDO1
SCHEMBL24027472 0.74 TSHR (0.36) TSHRKMT2ATRPA1ALDH1A1LMNA
SCHEMBL2261012 0.73 TSHR (0.39) TSHRKMT2AALDH1A1SLC6A2SLC6A3
SCHEMBL2252915 0.73 TSHR (0.41) TSHRKMT2AALDH1A1ADRA2BADRA2C
SCHEMBL12380718 0.72 FFAR1 (0.35) TSHRKMT2AALDH1A1SMN1; SMN2LMNA
SCHEMBL2227585 0.72 TSHR (0.40) TSHRKMT2AALDH1A1ADRA2BADRA2C
SCHEMBL4881254 0.71 MAOB (0.34) TSHRKMT2AALDH1A1CYP1A2CYP2C9
SCHEMBL6578072 0.71 LTA4H (0.44) TSHRALDH1A1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7037486-B1 Labelled phosphoinositides and analogues NUTRIMED BIOTECH (US) 2006-05-02 US disclosed